Affinity Data by PubMed id=30406661

PubMed code 30406661

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50218197 ((-)-beta-Sitosterol \| (24R)-Ethylcholest-5-en-3bet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	267	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Uncompetitive inhibition of human thrombin using T1637 as substrate by Michaelis-Menten plot analysis				J Nat Prod 81: 2521-2530 (2018) Article DOI: 10.1021/acs.jnatprod.8b00574 BindingDB Entry DOI: 10.7270/Q2BZ68RT
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50218197 ((-)-beta-Sitosterol \| (24R)-Ethylcholest-5-en-3bet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of thrombin in human washed platelets assessed as reduction in thrombin-induced platelet aggregation after 5 mins				J Nat Prod 81: 2521-2530 (2018) Article DOI: 10.1021/acs.jnatprod.8b00574 BindingDB Entry DOI: 10.7270/Q2BZ68RT
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50218197 ((-)-beta-Sitosterol \| (24R)-Ethylcholest-5-en-3bet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of thrombin in human platelet rich plasma assessed as reduction in thrombin-induced platelet aggregation after 5 mins				J Nat Prod 81: 2521-2530 (2018) Article DOI: 10.1021/acs.jnatprod.8b00574 BindingDB Entry DOI: 10.7270/Q2BZ68RT
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50218197 ((-)-beta-Sitosterol \| (24R)-Ethylcholest-5-en-3bet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of thrombin in human platelet rich plasma assessed as reduction in arachidonic acid-induced platelet aggregation after 5 mins				J Nat Prod 81: 2521-2530 (2018) Article DOI: 10.1021/acs.jnatprod.8b00574 BindingDB Entry DOI: 10.7270/Q2BZ68RT
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50218197 ((-)-beta-Sitosterol \| (24R)-Ethylcholest-5-en-3bet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Medicinal and Aromatic Plants Curated by ChEMBL					Assay Description Inhibition of thrombin in human platelet rich plasma assessed as reduction in ADP-induced platelet aggregation after 5 mins				J Nat Prod 81: 2521-2530 (2018) Article DOI: 10.1021/acs.jnatprod.8b00574 BindingDB Entry DOI: 10.7270/Q2BZ68RT
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%