Affinity Data by PubMed id=30655950

PubMed code 30655950

Found 116 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one \| CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM199181 (4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...) Show SMILES NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one \| CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503857 (CHEMBL4455412) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503854 (CHEMBL4577063) Show SMILES CC(=O)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503863 (CHEMBL4450751) Show SMILES Clc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503869 (CHEMBL4572268) Show SMILES Fc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP16 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human transmembrane domain deficient His-SUMO-tagged PARP16 expressed in Escherichia coli BL21 assessed as reduction in MARylation of H...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP16 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human transmembrane domain deficient His-SUMO-tagged PARP16 expressed in Escherichia coli BL21 assessed as reduction in MARylation of H...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50339016 (3,4-dihydroisoquinolin-1(2H)-one \| CHEMBL1688212) Show SMILES O=C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50339016 (3,4-dihydroisoquinolin-1(2H)-one \| CHEMBL1688212) Show SMILES O=C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503862 (CHEMBL4565850) Show SMILES O=C1NCCc2cc(ccc12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one \| CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM27682 (5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one \| CHE...) Show SMILES Cc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503852 (CHEMBL4470303) Show SMILES Brc1cccc2C(=O)NCCc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503861 (CHEMBL4565268) Show SMILES Brc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503861 (CHEMBL4565268) Show SMILES Brc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503851 (CHEMBL4585230) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503871 (CHEMBL4515501) Show SMILES O=C1NCCc2cc(Cc3ccccc3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503871 (CHEMBL4515501) Show SMILES O=C1NCCc2cc(Cc3ccccc3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503861 (CHEMBL4565268) Show SMILES Brc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503861 (CHEMBL4565268) Show SMILES Brc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503868 (CHEMBL4452747) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase TIPARP (Human)	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP7 assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescence assay				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase TIPARP (Human)	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP7 assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescence assay				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503856 (CHEMBL4559852) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccncc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503865 (CHEMBL4544104) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503859 (CHEMBL4524394) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP12 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of GFP-tagged human PARP12 expressed in HEK293T cells assessed as reduction in auto-MARylation after 60 mins in presence of 6-a-NAD+ by ch...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP8 (Homo sapiens)	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of GFP-tagged human PARP8 expressed in HEK293T cells assessed as reduction in auto-MARylation after 60 mins in presence of 6-a-NAD+ by che...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503855 (CHEMBL4513504) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503850 (CHEMBL4473649) Show SMILES Cc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503850 (CHEMBL4473649) Show SMILES Cc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503850 (CHEMBL4473649) Show SMILES Cc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503850 (CHEMBL4473649) Show SMILES Cc1ccc2C(=O)NCCc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503870 (CHEMBL4580007) Show SMILES O=C1NCCc2c1cccc2-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503866 (CHEMBL4589699) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503871 (CHEMBL4515501) Show SMILES O=C1NCCc2cc(Cc3ccccc3)ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503860 (CHEMBL4475063) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP14 catalytic-WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21 assessed as reduction in MARylation of SRP...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP14 catalytic-WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21 assessed as reduction in MARylation of SRP...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP15 catalytic domain assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluo...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP15 catalytic domain assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluo...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50339016 (3,4-dihydroisoquinolin-1(2H)-one \| CHEMBL1688212) Show SMILES O=C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50339016 (3,4-dihydroisoquinolin-1(2H)-one \| CHEMBL1688212) Show SMILES O=C1NCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP11 (Homo sapiens)	BDBM50503867 (CHEMBL4447011) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cncc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP5B catalytic domain (1 to 572 residues) assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP4 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP4 BRCT-catalytic domain (1 to 572 residues) assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence ...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP3 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human PARP3 assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescen...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human PARP2 assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescen...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human PARP1 assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescen...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of GFP-tagged human PARP10 expressed in HEK293T cells assessed as reduction in auto-MARylation after 3 hrs by Western blot analysis				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503853 (CHEMBL4545565) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1ccnc(c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of GFP-tagged human PARP10 expressed in HEK293T cells assessed as reduction in high molecular weight target protein MARylation after 3 hrs...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
Oregon Health and Science University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%