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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 4/G1/S-specific cyclin-D3 (Homo sapiens (Human)) | BDBM50528604 (CHEMBL4445335) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Inhibition of recombinant full length human CDK4/Cyclin D3 using Rb-fragmen as substrate incubated for 40 mins by [gamma-33P]-ATP based radiometric a... | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.044 BindingDB Entry DOI: 10.7270/Q2S46WF0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50528604 (CHEMBL4445335) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Inhibition of recombinant human VEGFR2 (790 to end residues) using myelin ba as substrate incubated for 40 mins by [gamma-33P]-ATP based radiometric ... | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.044 BindingDB Entry DOI: 10.7270/Q2S46WF0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50528604 (CHEMBL4445335) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Inhibition of recombinant human full length CDK2/CyclinA using as histone H1 substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scinti... | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.044 BindingDB Entry DOI: 10.7270/Q2S46WF0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM50528604 (CHEMBL4445335) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 247 | n/a | n/a | n/a | n/a | n/a | n/a |
Nankai University Curated by ChEMBL | Assay Description Inhibition of recombinant human full length CDK1/CyclinB using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scinti... | Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.044 BindingDB Entry DOI: 10.7270/Q2S46WF0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
