Affinity Data by PubMed id=31753802

PubMed code 31753802

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50538823 (CHEMBL4649334) Show SMILES COc1ccc(-c2cncn2-c2ccc(Br)cc2)c(OC)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50538821 (CHEMBL4645491) Show SMILES CC(C)(C)c1ccc(cc1)-c1cncn1C1CCCCC1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50538820 (CHEMBL4638855) Show SMILES COc1cccc(c1)-c1cncn1C1CCCCC1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50538819 (CHEMBL4642650) Show SMILES CCCCn1cncc1-c1ccc(cc1)C(C)(C)C Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50538822 (CHEMBL4633855) Show SMILES Fc1ccc(cc1)-c1cncn1-c1ccc(Br)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50538818 (CHEMBL4639852) Show SMILES CCCCn1cncc1-c1cccc(OC)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Witwatersrand Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase assessed as inhibition of interaction of HIV-1 IN with LEDGF/p75 (unknown origin) preincubated with enzyme for 30 mins ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115210 BindingDB Entry DOI: 10.7270/Q2348PZS
University of the Witwatersrand Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%