Affinity Data by PubMed id=31831383

PubMed code 31831383

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM50537996 (CHEMBL4632827) Show SMILES c1nn2cccnc2c1-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
Brigham Young University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length PIK3C3 (S282 to H879 residues) expressed in mammalian expression system at 10 uM by Kinomescan met...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126813 BindingDB Entry DOI: 10.7270/Q2SX6HQZ
Brigham Young University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50537996 (CHEMBL4632827) Show SMILES c1nn2cccnc2c1-c1nc2ccccc2s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a
Brigham Young University Curated by ChEMBL					Assay Description Binding affinity to wild-type human partial length JAK1 JH2 pseudokinase domain (R537 to D855 residues) expressed in mammalian expression system at 1...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126813 BindingDB Entry DOI: 10.7270/Q2SX6HQZ
Brigham Young University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%