Affinity Data by PubMed id=31902650

PubMed code 31902650

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM50541163 (CHEMBL4639024) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	470	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase repor...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115298 BindingDB Entry DOI: 10.7270/Q2DN48KB
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human))	BDBM20182 ((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Induction of human HMGCR-dCat-ELuc degradation expressed in HEK293 cells assessed as reduction in luciferase activity after 4 hrs by luciferase repor...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115298 BindingDB Entry DOI: 10.7270/Q2DN48KB
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%