Affinity Data by PubMed id=31999455

PubMed code 31999455

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
T-type calcium channel alpha 1G subunit (Mus musculus)	BDBM50514577 (CHEMBL3581591) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...				J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 BindingDB Entry DOI: 10.7270/Q24171DN
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
T-type calcium channel alpha 1G subunit (Mus musculus)	BDBM50514578 (CHEMBL4464354) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...				J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 BindingDB Entry DOI: 10.7270/Q24171DN
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
T-type calcium channel alpha 1G subunit (Mus musculus)	BDBM50090184 (CHEMBL3581573) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as inhibition of current amplitude at holding potential of -100 mV by whole c...				J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 BindingDB Entry DOI: 10.7270/Q24171DN
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM50514580 (CHEMBL4455355) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at Cav3.1 (unknown origin) expressed in HEK293T cells assessed as increase in current amplitude at holding potential of -100 mV by w...				J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 BindingDB Entry DOI: 10.7270/Q24171DN
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
T-type calcium channel alpha 1G subunit (Mus musculus)	BDBM50514579 (CHEMBL4575063) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Agonist activity at mouse Cav3.1 expressed in HEK293T cells assessed as increase in current amplitude at holding potential of -100 mV by whole cell e...				J Med Chem 63: 1709-1716 (2020) Article DOI: 10.1021/acs.jmedchem.9b02056 BindingDB Entry DOI: 10.7270/Q24171DN
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%