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PubMed code 32087465

Compile data set for download or QSAR
Found 51 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(GUINEA PIG)		BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1 |TLB:16:15:1:10.4.3|
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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 0.200n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membrane incubated for 2.5 hrs by scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50008984
PNG
(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3
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 0.390n/an/an/an/an/an/an/an/a


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Assay Description
Inhibition of sigma 1 receptor (unknown origin)

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564197
PNG
(CHEMBL4776178)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(F)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564176
PNG
(CHEMBL4797982)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564177
PNG
(CHEMBL4778918)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(C)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564193
PNG
(CHEMBL4789321)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564193
PNG
(CHEMBL4789321)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564186
PNG
(CHEMBL4797005)
Show SMILES CCC(=O)N(CCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564195
PNG
(CHEMBL4789528)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(C)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564175
PNG
(CHEMBL4788719)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccccc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1 |TLB:16:15:1:10.4.3|
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564178
PNG
(CHEMBL4785048)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564197
PNG
(CHEMBL4776178)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(F)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564183
PNG
(CHEMBL4797585)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)C(C)c1ccccc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564177
PNG
(CHEMBL4778918)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(C)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564187
PNG
(CHEMBL4777042)
Show SMILES CCC(=O)N(CCCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564184
PNG
(CHEMBL4792467)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)Cc1ccccc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564178
PNG
(CHEMBL4785048)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564176
PNG
(CHEMBL4797982)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564189
PNG
(CHEMBL4783182)
Show SMILES CCC(=O)N(CCN1CCC(CC1)c1ccccc1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564195
PNG
(CHEMBL4789528)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(C)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564194
PNG
(CHEMBL4788466)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(C)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564192
PNG
(CHEMBL4790304)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564175
PNG
(CHEMBL4788719)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccccc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564189
PNG
(CHEMBL4783182)
Show SMILES CCC(=O)N(CCN1CCC(CC1)c1ccccc1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564188
PNG
(CHEMBL4779284)
Show SMILES CCC(=O)N(CCCCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564186
PNG
(CHEMBL4797005)
Show SMILES CCC(=O)N(CCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
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Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564196
PNG
(CHEMBL4792476)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(F)cc1
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Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(GUINEA PIG)		BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1 |TLB:16:15:1:10.4.3|
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membrane incubated for 2.5 hrs by scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1 |TLB:16:15:1:10.4.3|
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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 62n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564191
PNG
(CHEMBL4787348)
Show SMILES CCC(=O)N(CCN1CCC(CCCc2ccccc2)CC1)c1ccc(OC)cc1
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 74n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564192
PNG
(CHEMBL4790304)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(OC)cc1
PDB

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 77n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564187
PNG
(CHEMBL4777042)
Show SMILES CCC(=O)N(CCCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
PDB

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 78n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564190
PNG
(CHEMBL4777040)
Show SMILES CCC(=O)N(CCN1CCC(CCc2ccccc2)CC1)c1ccc(OC)cc1
PDB

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 82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564194
PNG
(CHEMBL4788466)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(C)cc1
PDB

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 82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564196
PNG
(CHEMBL4792476)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccc(C)cc2)CC1)c1ccc(F)cc1
PDB

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 148n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564188
PNG
(CHEMBL4779284)
Show SMILES CCC(=O)N(CCCCCN1CCC(Cc2ccccc2)CC1)c1ccc(OC)cc1
PDB

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 165n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564180
PNG
(CHEMBL4790216)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccccn1
PDB

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 238n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564181
PNG
(CHEMBL4783373)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ncccc1F
PDB

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 253n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564185
PNG
(CHEMBL4781647)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)CCc1ccccc1
PDB

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 269n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564190
PNG
(CHEMBL4777040)
Show SMILES CCC(=O)N(CCN1CCC(CCc2ccccc2)CC1)c1ccc(OC)cc1
PDB

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 372n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564180
PNG
(CHEMBL4790216)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ccccn1
PDB

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 402n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564181
PNG
(CHEMBL4783373)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1ncccc1F
PDB

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 506n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564179
PNG
(CHEMBL4788563)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1cc(F)c(F)c(F)c1
PDB

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 573n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564184
PNG
(CHEMBL4792467)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)Cc1ccccc1
PDB

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 573n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564183
PNG
(CHEMBL4797585)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)C(C)c1ccccc1
PDB

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 694n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564182
PNG
(CHEMBL4794751)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1cccc(n1)C(F)(F)F
PDB

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 835n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50564191
PNG
(CHEMBL4787348)
Show SMILES CCC(=O)N(CCN1CCC(CCCc2ccccc2)CC1)c1ccc(OC)cc1
PDB

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 893n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting method

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564185
PNG
(CHEMBL4781647)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)CCc1ccccc1
PDB

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>2.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564179
PNG
(CHEMBL4788563)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1cc(F)c(F)c(F)c1
PDB

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>2.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))		BDBM50564182
PNG
(CHEMBL4794751)
Show SMILES CCC(=O)N(CCN1CCC(Cc2ccccc2)CC1)c1cccc(n1)C(F)(F)F
PDB

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>2.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-diprenorphin from human mu opioid receptor expressed in CHO cell membrane incubated for 150 mins by liquid scintillation countin...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112144
BindingDB Entry DOI: 10.7270/Q2WM1J54
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%