Found 61 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552350
(CHEMBL4746970)Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(c1)C#N | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552348
(CHEMBL4764083)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 114 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552357
(CHEMBL4780280)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 508 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552343
(CHEMBL4746530)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 267 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552354
(CHEMBL4799902)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 302 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR3 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552338
(CHEMBL4795522)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccc(Cl)cc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552339
(CHEMBL4744841)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552354
(CHEMBL4799902)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 42 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552332
(CHEMBL4797971)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552333
(CHEMBL4760570)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552340
(CHEMBL4789952)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccc(F)cc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552342
(CHEMBL4787053)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 56 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552344
(CHEMBL4748116)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)Cc2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552355
(CHEMBL4779008)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(cc1F)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552347
(CHEMBL4798021)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR2 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552347
(CHEMBL4798021)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR8 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 6
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR6 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552343
(CHEMBL4746530)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552349
(CHEMBL4792152)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552356
(CHEMBL4800540)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1C)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 306 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552330
(CHEMBL4745982)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 74 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552331
(CHEMBL4795139)Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 175 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552332
(CHEMBL4797971)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 229 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552346
(CHEMBL4777502)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 93 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552332
(CHEMBL4797971)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccc(Cl)o1 |t:7| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552349
(CHEMBL4792152)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 372 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50552330
(CHEMBL4745982)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552331
(CHEMBL4795139)Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552345
(CHEMBL4788523)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(Cl)cc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 217 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552349
(CHEMBL4792152)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 266 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552331
(CHEMBL4795139)Show SMILES Cc1nc(cs1)C(=O)Nc1cc(F)c(cc1C)N1C(=O)C2=C(CCCC2)C1=O |t:22| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552347
(CHEMBL4798021)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(Cl)c2C1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 98 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552330
(CHEMBL4745982)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552358
(CHEMBL4787147)Show SMILES CC1(C)C2C1C(=O)N(C2=O)c1ccc(NC(=O)c2ccccn2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Negative allosteric modulation of human mGluR1 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552335
(CHEMBL4752766)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)CC3(CCCC3)CC2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.98E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552336
(CHEMBL4763120)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)c1F |t:18| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552337
(CHEMBL4744409)Show SMILES [H][C@@]12CC=CC[C@]1([H])C(=O)N(C2=O)c1cc(F)c(NC(=O)c2occc2C)c(F)c1F |r,c:3| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552341
(CHEMBL4782646)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccc(Cl)cc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 99 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552348
(CHEMBL4764083)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552333
(CHEMBL4760570)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552354
(CHEMBL4799902)Show SMILES Cc1ccoc1C(=O)Nc1c(F)cc(N2C(=O)c3ccccc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 212 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552333
(CHEMBL4760570)Show SMILES Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1NC(=O)c1ccco1 |t:7| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 377 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552342
(CHEMBL4787053)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 201 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552343
(CHEMBL4746530)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(F)c3C2=O)c(F)c1F | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 487 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50552330
(CHEMBL4745982)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 189 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of mGluR8 (unknown origin) by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552334
(CHEMBL4757473)Show SMILES [H][C@]12C[C@]([H])(C=C1)C1C2C(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1 |r,c:5| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552346
(CHEMBL4777502)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 132 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552351
(CHEMBL4755776)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccccc3C2=O)c(F)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552352
(CHEMBL4796783)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 78 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50143059
(CHEMBL3758746)Show SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(C)cc2C1=O Show InChI InChI=1S/C12H11Cl2N5O2/c1-6-10(11(20)17-12(15)16-6)19(18-21)5-7-2-3-8(13)9(14)4-7/h2-4H,5H2,1H3,(H3,15,16,17,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552342
(CHEMBL4787053)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3cccc(Cl)c3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 187 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552348
(CHEMBL4764083)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2cccc(F)c2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 113 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50552330
(CHEMBL4745982)Show SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 128 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50552346
(CHEMBL4777502)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(cc1C)N1C(=O)c2ccc(C)cc2C1=O | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 106 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50552353
(CHEMBL4742005)Show SMILES Cc1ccoc1C(=O)Nc1cc(F)c(N2C(=O)c3ccccc3C2=O)c(F)c1F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 591 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2020.127724 BindingDB Entry DOI: 10.7270/Q2WS8XWG |
More data for this Ligand-Target Pair | |