Affinity Data by PubMed id=3806568

PubMed code 3806568

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025549 (6-Chloro-3-phenyl-pyran-2-one \| CHEMBL274455) Show SMILES Clc1ccc(-c2ccccc2)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025557 (6-Chloro-5-phenyl-pyran-2-one \| CHEMBL16220) Show SMILES Clc1oc(=O)ccc1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025547 (5-Butyl-6-chloro-pyran-2-one \| CHEMBL16637) Show SMILES CCCCc1ccc(=O)oc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025550 (6-Chloro-5-ethyl-pyran-2-one \| CHEMBL278224) Show SMILES CCc1ccc(=O)oc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025556 (5-Benzyl-6-bromo-pyran-2-one \| CHEMBL16054) Show SMILES Brc1oc(=O)ccc1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025559 (5-Benzyl-6-chloro-pyran-2-one \| CHEMBL16064) Show SMILES Clc1oc(=O)ccc1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025548 (6-Chloro-5-naphthalen-2-ylmethyl-pyran-2-one \| CHE...) Show SMILES Clc1oc(=O)ccc1Cc1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025546 (5-Phenyl-pyran-2-one \| CHEMBL278453) Show SMILES O=c1ccc(co1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025563 (3-Benzyl-6-chloro-pyran-2-one \| CHEMBL16433) Show SMILES Clc1ccc(Cc2ccccc2)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025562 (6-Chloro-3-naphthalen-1-ylmethyl-pyran-2-one \| CHE...) Show SMILES Clc1ccc(Cc2cccc3ccccc23)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025560 (3-Benzyl-6-bromo-pyran-2-one \| CHEMBL279537) Show SMILES Brc1ccc(Cc2ccccc2)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025543 (3-Benzyl-pyran-2-one \| CHEMBL277772) Show SMILES O=c1occcc1Cc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025551 (3-Naphthalen-2-ylmethyl-pyran-2-one \| CHEMBL16202) Show SMILES O=c1occcc1Cc1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.67E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025553 (5-Benzyl-pyran-2-one \| CHEMBL276542) Show SMILES O=c1ccc(Cc2ccccc2)co1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.95E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025555 (3-Naphthalen-1-ylmethyl-pyran-2-one \| CHEMBL275180) Show SMILES O=c1occcc1Cc1cccc2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.24E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025544 (6-Chloro-4-phenyl-pyran-2-one \| CHEMBL16485) Show SMILES Clc1cc(cc(=O)o1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	3.82E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025545 (4-Phenyl-pyran-2-one \| CHEMBL16638) Show SMILES O=c1cc(cco1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	4.95E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025561 (6-Chloro-3-naphthalen-2-ylmethyl-pyran-2-one \| CHE...) Show SMILES Clc1ccc(Cc2ccc3ccccc3c2)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025552 (6-Chloro-3-ethyl-pyran-2-one \| CHEMBL16055) Show SMILES CCc1ccc(Cl)oc1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.85E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025554 (3-Benzyl-6-trifluoromethyl-pyran-2-one \| CHEMBL160...) Show SMILES FC(F)(F)c1ccc(Cc2ccccc2)c(=O)o1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.27E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50025564 (3-Butyl-6-chloro-pyran-2-one \| CHEMBL16006) Show SMILES CCCCc1ccc(Cl)oc1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.98E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards alpha-chymotrypsin from bovine pancreas.				J Med Chem 29: 1159-63 (1987) BindingDB Entry DOI: 10.7270/Q27080D6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%