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Articleid 50028905

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thromboxane A2 receptor


(RAT)
BDBM50212318
PNG
(BMS-180291 | Ifetroban)
Show SMILES CCCCCNC(=O)c1coc(n1)[C@@H]1[C@H]2CC[C@H](O2)[C@@H]1Cc1ccccc1CCC(O)=O |TLB:20:19:18:16.15,THB:11:13:18:16.15|
Show InChI InChI=1S/C25H32N2O5/c1-2-3-6-13-26-24(30)19-15-31-25(27-19)23-18(20-10-11-21(23)32-20)14-17-8-5-4-7-16(17)9-12-22(28)29/h4-5,7-8,15,18,20-21,23H,2-3,6,9-14H2,1H3,(H,26,30)(H,28,29)/t18-,20-,21+,23-/m0/s1
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PC cid
PC sid
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Similars

Article
n/an/an/a 4n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ 29,548 radioligand binding to thromboxane A2 (TXA2) receptor of human platelet membranes


Bioorg Med Chem Lett 2: 73-76 (1992)


Article DOI: 10.1016/S0960-894X(00)80658-7
BindingDB Entry DOI: 10.7270/Q25T3KCJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%