Found 8 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM82025
(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)Show InChI InChI=1S/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A1 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM50011840
(1-Methyl-8-phenyl-3-propyl-3,7-dihydro-purine-2,6-...)Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A1 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM50011834
(3-Methyl-8-phenyl-1-propyl-3,7-dihydro-purine-2,6-...)Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A1 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A1
(Rattus norvegicus (rat)) | BDBM82015
(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)Show InChI InChI=1S/C13H12N4O2/c1-16-11-9(12(18)17(2)13(16)19)14-10(15-11)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,14,15) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A1 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a/A2b
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50011840
(1-Methyl-8-phenyl-3-propyl-3,7-dihydro-purine-2,6-...)Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-13-11(14(20)18(2)15(19)21)16-12(17-13)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A2 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a/A2b
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM82025
(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)Show InChI InChI=1S/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A2 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a/A2b
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50011834
(3-Methyl-8-phenyl-1-propyl-3,7-dihydro-purine-2,6-...)Show InChI InChI=1S/C15H16N4O2/c1-3-9-19-14(20)11-13(18(2)15(19)21)17-12(16-11)10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3,(H,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 553 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A2 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Adenosine receptor A2a/A2b
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM82015
(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)Show InChI InChI=1S/C13H12N4O2/c1-16-11-9(12(18)17(2)13(16)19)14-10(15-11)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 644 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity towards adenosine A2 receptor |
Bioorg Med Chem Lett 2: 1199-1200 (1992)
Article DOI: 10.1016/S0960-894X(00)80213-9
BindingDB Entry DOI: 10.7270/Q2NS0TT4 |
More data for this
Ligand-Target Pair | |
Search and Browse
