Affinity Data by BDB articleid=50028942

Articleid 50028942

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280269 (3-[2-(4-Amino-benzylcarbamoyl)-ethyl]-4,6-dichloro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50061396 (4,6-Dichloro-3-(2-phenylcarbamoyl-ethyl)-1H-indole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004952 (3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280277 (3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid \|...) Show SMILES NC(=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50009079 (6-Chloro-3-methoxycarbonylmethyl-1H-indole-2-carbo...) Show SMILES COC(=O)Cc1c([nH]c2cc(Cl)ccc12)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280272 (6-Chloro-3-hydroxymethyl-1H-indole-2-carboxylic ac...) Show SMILES OCc1c([nH]c2cc(Cl)ccc12)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280278 ((R)-6-Chloro-1,2-dihydro-indole-2,3,3-tricarboxyli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280270 ((2R,3R)-3-Carbamoyl-6-chloro-2,3-dihydro-1H-indole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280274 ((2R,3R)-6-Chloro-2,3-dihydro-1H-indole-2,3-dicarbo...) Show SMILES OC(=O)[C@@H]1Nc2cc(Cl)ccc2[C@H]1C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280275 ((2R,3R)-6-Chloro-3-hydroxymethyl-2,3-dihydro-1H-in...) Show SMILES OC[C@H]1[C@@H](Nc2cc(Cl)ccc12)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280273 ((2R,3R)-3-Benzoyloxymethyl-6-chloro-2,3-dihydro-1H...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280276 ((2R,3R)-3-Carboxymethyl-6-chloro-2,3-dihydro-1H-in...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50280271 ((2R,3R)-6-Chloro-2,3-dihydro-1H-indole-2,3-dicarbo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranes				Bioorg Med Chem Lett 2: 1627-1630 (1992) Article DOI: 10.1016/S0960-894X(00)80444-8 BindingDB Entry DOI: 10.7270/Q22V2G1V
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%