BindingDB logo
myBDB logout

Articleid 50029023

Compile data set for download or QSAR
Found 20 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038175
PNG
((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...)
Show SMILES N[C@@H]1[C@H](O)CN(O)C1=O
Show InChI InChI=1S/C4H8N2O3/c5-3-2(7)1-6(9)4(3)8/h2-3,7,9H,1,5H2/t2-,3-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 1.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038169
PNG
((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)
Show SMILES C[C@@H]1CN(O)C(=O)[C@@H]1N
Show InChI InChI=1S/C5H10N2O2/c1-3-2-7(9)5(8)4(3)6/h3-4,9H,2,6H2,1H3/t3-,4-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 1.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038169
PNG
((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)
Show SMILES C[C@@H]1CN(O)C(=O)[C@@H]1N
Show InChI InChI=1S/C5H10N2O2/c1-3-2-7(9)5(8)4(3)6/h3-4,9H,2,6H2,1H3/t3-,4-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 1.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038159
PNG
((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Show SMILES N[C@@H]1CCN(O)C1=O
Show InChI InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2/t3-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 1.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038159
PNG
((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)
Show SMILES N[C@@H]1CCN(O)C1=O
Show InChI InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2/t3-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 1.25E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280800
PNG
((3R,4R)-3-Amino-4-ethyl-1-hydroxy-pyrrolidin-2-one...)
Show SMILES CC[C@@H]1CN(O)C(=O)[C@@H]1N
Show InChI InChI=1S/C6H12N2O2/c1-2-4-3-8(10)6(9)5(4)7/h4-5,10H,2-3,7H2,1H3/t4-,5-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 1.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50038157
PNG
(6-Hydroxy-2,6-diaza-bicyclo[3.2.1]octan-7-one | CH...)
Show SMILES ON1C2CC(NCC2)C1=O |TLB:0:1:3:5.7.6,THB:9:8:3:5.7.6|
Show InChI InChI=1S/C6H10N2O2/c9-6-5-3-4(8(6)10)1-2-7-5/h4-5,7,10H,1-3H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 1.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50403116
PNG
(CHEMBL2115569)
Show SMILES C[C@@H]1C2CCNC1C(=O)N2O |r,TLB:10:9:1:5.3.4,0:1:7.9:5.3.4,THB:8:7:1:5.3.4|
Show InChI InChI=1S/C7H12N2O2/c1-4-5-2-3-8-6(4)7(10)9(5)11/h4-6,8,11H,2-3H2,1H3/t4-,5?,6?/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 4.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280796
PNG
((3S,4S)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)
Show SMILES C[C@H]1CN(O)C(=O)[C@H]1N
Show InChI InChI=1S/C5H10N2O2/c1-3-2-7(9)5(8)4(3)6/h3-4,9H,2,6H2,1H3/t3-,4-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 8.60E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280802
PNG
((3R,4R)-3-Amino-1-hydroxy-4-hydroxymethyl-pyrrolid...)
Show SMILES N[C@@H]1[C@H](CO)CN(O)C1=O
Show InChI InChI=1S/C5H10N2O3/c6-4-3(2-8)1-7(10)5(4)9/h3-4,8,10H,1-2,6H2/t3-,4+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280793
PNG
((3R,4R)-3-Amino-1-hydroxy-4-phenyl-pyrrolidin-2-on...)
Show SMILES N[C@@H]1[C@@H](CN(O)C1=O)c1ccccc1
Show InChI InChI=1S/C10H12N2O2/c11-9-8(6-12(14)10(9)13)7-4-2-1-3-5-7/h1-5,8-9,14H,6,11H2/t8-,9+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280792
PNG
(3-Hydroxy-3,6-diaza-bicyclo[3.2.1]octan-4-one | CH...)
Show SMILES ON1CC2CNC(C2)C1=O |TLB:9:8:7:5.4,0:1:7:5.4|
Show InChI InChI=1S/C6H10N2O2/c9-6-5-1-4(2-7-5)3-8(6)10/h4-5,7,10H,1-3H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50403115
PNG
(CHEMBL2115541)
Show SMILES C[C@H]1C2CCNC1C(=O)N2O |r,TLB:10:9:1:5.3.4,0:1:7.9:5.3.4,THB:8:7:1:5.3.4|
Show InChI InChI=1S/C7H12N2O2/c1-4-5-2-3-8-6(4)7(10)9(5)11/h4-6,8,11H,2-3H2,1H3/t4-,5?,6?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280797
PNG
(5-Hydroxy-hexahydro-pyrrolo[3,4-b]pyrrol-6-one | C...)
Show SMILES ON1CC2CCNC2C1=O
Show InChI InChI=1S/C6H10N2O2/c9-6-5-4(1-2-7-5)3-8(6)10/h4-5,7,10H,1-3H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280801
PNG
((3R,4R)-3-Amino-1-hydroxy-4-(2-hydroxy-ethyl)-pyrr...)
Show SMILES N[C@@H]1[C@H](CCO)CN(O)C1=O
Show InChI InChI=1S/C6H12N2O3/c7-5-4(1-2-9)3-8(11)6(5)10/h4-5,9,11H,1-3,7H2/t4-,5-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280794
PNG
((3R,4S)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)
Show SMILES C[C@H]1CN(O)C(=O)[C@@H]1N
Show InChI InChI=1S/C5H10N2O2/c1-3-2-7(9)5(8)4(3)6/h3-4,9H,2,6H2,1H3/t3-,4+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280798
PNG
((3R,4R)-3-Amino-4-propyl-pyrrolidin-2-one | CHEMBL...)
Show SMILES CCC[C@@H]1CNC(=O)[C@@H]1N
Show InChI InChI=1S/C7H14N2O/c1-2-3-5-4-9-7(10)6(5)8/h5-6H,2-4,8H2,1H3,(H,9,10)/t5-,6-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280795
PNG
(7-Hydroxy-2,7-diaza-bicyclo[3.3.1]nonan-8-one | CH...)
Show SMILES ON1CC2CCNC(C2)C1=O |TLB:10:9:8:6.5.4,0:1:8:6.5.4|
Show InChI InChI=1S/C7H12N2O2/c10-7-6-3-5(1-2-8-6)4-9(7)11/h5-6,8,11H,1-4H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50280803
PNG
((3R,4S)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...)
Show SMILES N[C@@H]1[C@@H](O)CN(O)C1=O
Show InChI InChI=1S/C4H8N2O3/c5-3-2(7)1-6(9)4(3)8/h2-3,7,9H,1,5H2/t2-,3+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 3.13E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50212605
PNG
(CHEMBL351464)
Show SMILES NC1CCN(O)C1=O
Show InChI InChI=1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
n/an/a 3.39E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine binding to rat cortical membranes

Bioorg Med Chem Lett 3: 71-76 (1993)


Article DOI: 10.1016/S0960-894X(00)80094-3
BindingDB Entry DOI: 10.7270/Q2RB74HX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%