Affinity Data by BDB articleid=50029295

Articleid 50029295

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50450086 (CHEMBL2114043) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50450086 (CHEMBL2114043) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283069 ((S)-3-Hydroxy-2-((S)-4-methyl-2-{(S)-3-methyl-2-[(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283064 (2-(2-{(S)-1-[(S)-1-((S)-1-Carboxy-2-hydroxy-ethylc...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283063 ((4E,8E)-2-((S)-3-{1-[1-((S)-1-(S)-Carboxy-2-hydrox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283062 ((4E,8E)-2-((S)-4-{1-[1-((S)-1-(S)-Carboxy-2-hydrox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50450085 (CHEMBL2114046) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283068 ((S)-4-{1-[1-((S)-1-(S)-Carboxy-2-hydroxy-ethylcarb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283066 ((4E,8E)-2-({1-[1-((S)-1-(S)-Carboxy-2-hydroxy-ethy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283070 (2-(2-{(S)-1-[(S)-1-((S)-1-Carboxy-2-hydroxy-ethylc...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50450084 (CHEMBL2115115) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283071 (2-((S)-2-tert-Butoxycarbonylamino-2-{(S)-1-[(S)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283067 ((S)-3-Hydroxy-2-{(S)-4-methyl-2-[(S)-3-methyl-2-((...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50283065 ((E)-2-(2-{(S)-1-[(S)-1-((S)-1-Carboxy-2-hydroxy-et...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ras Farnesyltransferase				Bioorg Med Chem Lett 4: 2107-2112 (1994) Article DOI: 10.1016/S0960-894X(01)80111-6 BindingDB Entry DOI: 10.7270/Q2ZW1KTF
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%