Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human)) | BDBM50066068 (CHEMBL28853 | N-Acenaphthen-5-yl-N'-(4-methoxy-nap...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channel | Bioorg Med Chem Lett 5: 2259-2262 (1995) Article DOI: 10.1016/0960-894X(95)00392-7 BindingDB Entry DOI: 10.7270/Q200022B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human)) | BDBM50285278 (CHEMBL307395 | N,N'-Di-acenaphthen-5-yl-guanidine) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channel | Bioorg Med Chem Lett 5: 2259-2262 (1995) Article DOI: 10.1016/0960-894X(95)00392-7 BindingDB Entry DOI: 10.7270/Q200022B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human)) | BDBM30705 (CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channel | Bioorg Med Chem Lett 5: 2259-2262 (1995) Article DOI: 10.1016/0960-894X(95)00392-7 BindingDB Entry DOI: 10.7270/Q200022B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human)) | BDBM50066430 (2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | Article | n/a | n/a | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Blockade of synaptosomal sodium channels, inhibition of [14C]-guanidinium ion flux into CHO cells expressing Type II sodium channel | Bioorg Med Chem Lett 5: 2259-2262 (1995) Article DOI: 10.1016/0960-894X(95)00392-7 BindingDB Entry DOI: 10.7270/Q200022B | |||||||||||
More data for this Ligand-Target Pair |