Found 5 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-galactosidase
(Aspergillus niger) | BDBM50287006
(Azepane-3,4,5,6-tetraol | CHEMBL13922)Show InChI InChI=1S/C6H13NO4/c8-3-1-7-2-4(9)6(11)5(3)10/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
| 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibition of beta-galactosidase from aspergillus niger. |
Bioorg Med Chem Lett 6: 1117-1122 (1996)
Article DOI: 10.1016/0960-894X(96)00183-7
BindingDB Entry DOI: 10.7270/Q2M32VQR |
More data for this
Ligand-Target Pair | |
Lysosomal acid glucosylceramidase
(Homo sapiens (Human)) | BDBM50287006
(Azepane-3,4,5,6-tetraol | CHEMBL13922)Show InChI InChI=1S/C6H13NO4/c8-3-1-7-2-4(9)6(11)5(3)10/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
| 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibition of beta-glucosidase from sweet almonds. |
Bioorg Med Chem Lett 6: 1117-1122 (1996)
Article DOI: 10.1016/0960-894X(96)00183-7
BindingDB Entry DOI: 10.7270/Q2M32VQR |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Tissue alpha-L-fucosidase
(Homo sapiens (Human)) | BDBM50287007
(1-Benzyl-azepane-3,4,5,6-tetraol | CHEMBL418537)Show SMILES O[C@@H]1CN(Cc2ccccc2)C[C@@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C13H19NO4/c15-10-7-14(6-9-4-2-1-3-5-9)8-11(16)13(18)12(10)17/h1-5,10-13,15-18H,6-8H2/t10-,11-,12-,13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| 2.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibition of alpha-fucosidase from bovine kidney. |
Bioorg Med Chem Lett 6: 1117-1122 (1996)
Article DOI: 10.1016/0960-894X(96)00183-7
BindingDB Entry DOI: 10.7270/Q2M32VQR |
More data for this
Ligand-Target Pair | |
Lysosomal alpha-glucosidase
(Homo sapiens (Human)) | BDBM50287006
(Azepane-3,4,5,6-tetraol | CHEMBL13922)Show InChI InChI=1S/C6H13NO4/c8-3-1-7-2-4(9)6(11)5(3)10/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1 | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
| 2.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibition of alpha-glucosidase from yeast. |
Bioorg Med Chem Lett 6: 1117-1122 (1996)
Article DOI: 10.1016/0960-894X(96)00183-7
BindingDB Entry DOI: 10.7270/Q2M32VQR |
More data for this
Ligand-Target Pair | |
Alpha-galactosidase A
(Homo sapiens (Human)) | BDBM50287006
(Azepane-3,4,5,6-tetraol | CHEMBL13922)Show InChI InChI=1S/C6H13NO4/c8-3-1-7-2-4(9)6(11)5(3)10/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
| 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for inhibition of alpha-galactosidase from green coffee beans. |
Bioorg Med Chem Lett 6: 1117-1122 (1996)
Article DOI: 10.1016/0960-894X(96)00183-7
BindingDB Entry DOI: 10.7270/Q2M32VQR |
More data for this
Ligand-Target Pair | |
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