Found 11 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059429
((S)-6-Amino-2-[(S)-3-hydroxy-2-((R)-2-{4-[4-(2-met...)Show SMILES C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25-,30+,31+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059427
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25?,30-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059419
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C35H56N6O4/c1-3-30(29-17-15-28(16-18-29)13-8-10-23-41-24-22-37-26(41)2)33(43)40-32(25-42)35(45)39-31(14-7-9-20-36)34(44)38-21-19-27-11-5-4-6-12-27/h15-18,22,24,27,30-32,42H,3-14,19-21,23,25,36H2,1-2H3,(H,38,44)(H,39,45)(H,40,43)/t30?,31-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50034993
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES Cc1nccn1CCCCc1ccc(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1 Show InChI InChI=1S/C33H52N6O4/c1-25-35-20-22-39(25)21-8-6-11-27-13-15-28(16-14-27)23-31(41)37-30(24-40)33(43)38-29(12-5-7-18-34)32(42)36-19-17-26-9-3-2-4-10-26/h13-16,20,22,26,29-30,40H,2-12,17-19,21,23-24,34H2,1H3,(H,36,42)(H,37,41)(H,38,43)/t29-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059428
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CCCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C36H58N6O4/c1-3-11-31(30-18-16-29(17-19-30)14-8-10-24-42-25-23-38-27(42)2)34(44)41-33(26-43)36(46)40-32(15-7-9-21-37)35(45)39-22-20-28-12-5-4-6-13-28/h16-19,23,25,28,31-33,43H,3-15,20-22,24,26,37H2,1-2H3,(H,39,45)(H,40,46)(H,41,44)/t31?,32-,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059428
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CCCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C36H58N6O4/c1-3-11-31(30-18-16-29(17-19-30)14-8-10-24-42-25-23-38-27(42)2)34(44)41-33(26-43)36(46)40-32(15-7-9-21-37)35(45)39-22-20-28-12-5-4-6-13-28/h16-19,23,25,28,31-33,43H,3-15,20-22,24,26,37H2,1-2H3,(H,39,45)(H,40,46)(H,41,44)/t31?,32-,33-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against human N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059419
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CCC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C35H56N6O4/c1-3-30(29-17-15-28(16-18-29)13-8-10-23-41-24-22-37-26(41)2)33(43)40-32(25-42)35(45)39-31(14-7-9-20-36)34(44)38-21-19-27-11-5-4-6-12-27/h15-18,22,24,27,30-32,42H,3-14,19-21,23,25,36H2,1-2H3,(H,38,44)(H,39,45)(H,40,43)/t30?,31-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against human N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059427
((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)Show SMILES CC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25?,30-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against human N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059429
((S)-6-Amino-2-[(S)-3-hydroxy-2-((R)-2-{4-[4-(2-met...)Show SMILES C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25-,30+,31+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against human N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059434
((S)-6-Amino-2-[(S)-3-hydroxy-2-((S)-2-{4-[4-(2-met...)Show SMILES C[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25-,30-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against human N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase 1
(Homo sapiens (Human)) | BDBM50059434
((S)-6-Amino-2-[(S)-3-hydroxy-2-((S)-2-{4-[4-(2-met...)Show SMILES C[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCn2ccnc2C)cc1 Show InChI InChI=1S/C34H54N6O4/c1-25(29-16-14-28(15-17-29)12-7-9-22-40-23-21-36-26(40)2)32(42)39-31(24-41)34(44)38-30(13-6-8-19-35)33(43)37-20-18-27-10-4-3-5-11-27/h14-17,21,23,25,27,30-31,41H,3-13,18-20,22,24,35H2,1-2H3,(H,37,43)(H,38,44)(H,39,42)/t25-,30-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT) |
Bioorg Med Chem Lett 6: 1977-1982 (1996)
Article DOI: 10.1016/0960-894X(96)00354-X
BindingDB Entry DOI: 10.7270/Q2TH8MPP |
More data for this
Ligand-Target Pair | |
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