Found 22 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289968
(4-[1-Ethyl-4-(4-fluoro-phenyl)-5-trifluoromethyl-1...)Show SMILES CCn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H15F4N3O2S/c1-2-25-17(18(20,21)22)15(11-3-7-13(19)8-4-11)16(24-25)12-5-9-14(10-6-12)28(23,26)27/h3-10H,2H2,1H3,(H2,23,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289969
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CCc2ccccc2)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C25H20F4N2O2S/c1-34(32,33)21-13-9-19(10-14-21)23-22(18-7-11-20(26)12-8-18)24(25(27,28)29)31(30-23)16-15-17-5-3-2-4-6-17/h2-14H,15-16H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289977
(1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC=C)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H16F4N2O2S/c1-3-12-26-19(20(22,23)24)17(13-4-8-15(21)9-5-13)18(25-26)14-6-10-16(11-7-14)29(2,27)28/h3-11H,1,12H2,2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50029616
(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289975
(1-Ethyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CCn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H16F4N2O2S/c1-3-25-18(19(21,22)23)16(12-4-8-14(20)9-5-12)17(24-25)13-6-10-15(11-7-13)28(2,26)27/h4-11H,3H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289970
(CHEMBL65793 | [4-(4-Fluoro-phenyl)-3-(4-methanesul...)Show SMILES CCOC(=O)Cn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C21H18F4N2O4S/c1-3-31-17(28)12-27-20(21(23,24)25)18(13-4-8-15(22)9-5-13)19(26-27)14-6-10-16(11-7-14)32(2,29)30/h4-11H,3,12H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289973
(2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC(=O)Nc2ccccc2)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C25H19F4N3O3S/c1-36(34,35)20-13-9-17(10-14-20)23-22(16-7-11-18(26)12-8-16)24(25(27,28)29)32(31-23)15-21(33)30-19-5-3-2-4-6-19/h2-14H,15H2,1H3,(H,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289976
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CCc2ccccc2)cc1-c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN2O2S/c1-30(28,29)22-13-9-20(10-14-22)24-23(19-7-11-21(25)12-8-19)17-27(26-24)16-15-18-5-3-2-4-6-18/h2-14,17H,15-16H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289968
(4-[1-Ethyl-4-(4-fluoro-phenyl)-5-trifluoromethyl-1...)Show SMILES CCn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H15F4N3O2S/c1-2-25-17(18(20,21)22)15(11-3-7-13(19)8-4-11)16(24-25)12-5-9-14(10-6-12)28(23,26)27/h3-10H,2H2,1H3,(H2,23,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289975
(1-Ethyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CCn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H16F4N2O2S/c1-3-25-18(19(21,22)23)16(12-4-8-14(20)9-5-12)17(24-25)13-6-10-15(11-7-13)28(2,26)27/h4-11H,3H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289971
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1n[nH]cc1-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN2O2S/c1-22(20,21)14-8-4-12(5-9-14)16-15(10-18-19-16)11-2-6-13(17)7-3-11/h2-10H,1H3,(H,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289973
(2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC(=O)Nc2ccccc2)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C25H19F4N3O3S/c1-36(34,35)20-13-9-17(10-14-20)23-22(16-7-11-18(26)12-8-16)24(25(27,28)29)32(31-23)15-21(33)30-19-5-3-2-4-6-19/h2-14H,15H2,1H3,(H,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289977
(1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC=C)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H16F4N2O2S/c1-3-12-26-19(20(22,23)24)17(13-4-8-15(21)9-5-13)18(25-26)14-6-10-16(11-7-14)29(2,27)28/h3-11H,1,12H2,2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289974
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1n[nH]c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H12F4N2O2S/c1-26(24,25)13-8-4-11(5-9-13)15-14(10-2-6-12(18)7-3-10)16(23-22-15)17(19,20)21/h2-9H,1H3,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289974
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1n[nH]c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H12F4N2O2S/c1-26(24,25)13-8-4-11(5-9-13)15-14(10-2-6-12(18)7-3-10)16(23-22-15)17(19,20)21/h2-9H,1H3,(H,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289976
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CCc2ccccc2)cc1-c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN2O2S/c1-30(28,29)22-13-9-20(10-14-22)24-23(19-7-11-21(25)12-8-19)17-27(26-24)16-15-18-5-3-2-4-6-18/h2-14,17H,15-16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289971
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1n[nH]cc1-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN2O2S/c1-22(20,21)14-8-4-12(5-9-14)16-15(10-18-19-16)11-2-6-13(17)7-3-11/h2-10H,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289972
(1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC=C)cc1-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN2O2S/c1-3-12-22-13-18(14-4-8-16(20)9-5-14)19(21-22)15-6-10-17(11-7-15)25(2,23)24/h3-11,13H,1,12H2,2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289969
(4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CCc2ccccc2)c(c1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C25H20F4N2O2S/c1-34(32,33)21-13-9-19(10-14-21)23-22(18-7-11-20(26)12-8-18)24(25(27,28)29)31(30-23)16-15-17-5-3-2-4-6-17/h2-14H,15-16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50289972
(1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nn(CC=C)cc1-c1ccc(F)cc1 Show InChI InChI=1S/C19H17FN2O2S/c1-3-12-22-13-18(14-4-8-16(20)9-5-14)19(21-22)15-6-10-17(11-7-15)25(2,23)24/h3-11,13H,1,12H2,2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human Prostaglandin G/H synthase 2 |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50029616
(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration of the compound against recombinant human COX-1 (Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM50289970
(CHEMBL65793 | [4-(4-Fluoro-phenyl)-3-(4-methanesul...)Show SMILES CCOC(=O)Cn1nc(c(c1C(F)(F)F)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C21H18F4N2O4S/c1-3-31-17(28)12-27-20(21(23,24)25)18(13-4-8-15(22)9-5-13)19(26-27)14-6-10-16(11-7-14)32(2,29)30/h4-11H,3,12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
In vitro inhibitory concentration against human COX-1(Cyclooxygenase-1) |
Bioorg Med Chem Lett 7: 2121-2124 (1997)
Article DOI: 10.1016/S0960-894X(97)00372-7
BindingDB Entry DOI: 10.7270/Q2H9956J |
More data for this
Ligand-Target Pair | |
Search and Browse
