BindingDB logo
myBDB logout

Articleid 50034773

Compile data set for download or QSAR
Found 12 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50185321
PNG
(6-cyano-7-nitroquinoxaline-2,3-dione | 7-nitro-2,3...)
Show SMILES [O-][N+](=O)c1cc2=NC(=O)C(=O)N=c2cc1C#N |c:11,t:5|
Show InChI InChI=1S/C9H2N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents
Article
n/an/a 7.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283027
PNG
((7-Chloro-2-oxo-1,2-dihydro-quinolin-4-ylmethyl)-p...)
Show SMILES OP(O)(=O)Cc1cc(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C10H9ClNO4P/c11-7-1-2-8-6(5-17(14,15)16)3-10(13)12-9(8)4-7/h1-4H,5H2,(H,12,13)(H2,14,15,16)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283032
PNG
((5,7-Dichloro-2-oxo-1,2-dihydro-quinolin-4-ylmethy...)
Show SMILES OP(O)(=O)Cc1cc(=O)[nH]c2cc(Cl)cc(Cl)c12
Show InChI InChI=1S/C10H8Cl2NO4P/c11-6-2-7(12)10-5(4-18(15,16)17)1-9(14)13-8(10)3-6/h1-3H,4H2,(H,13,14)(H2,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 2.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283023
PNG
((7-Iodo-2-oxo-1,2-dihydro-quinolin-4-ylmethyl)-pho...)
Show SMILES OP(O)(=O)Cc1cc(=O)[nH]c2cc(I)ccc12
Show InChI InChI=1S/C10H9INO4P/c11-7-1-2-8-6(5-17(14,15)16)3-10(13)12-9(8)4-7/h1-4H,5H2,(H,12,13)(H2,14,15,16)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a 3.70E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283029
PNG
(7-Chloro-4-phosphonomethyl-quinoline-2-carboxylic ...)
Show SMILES OC(=O)c1cc(CP(O)(O)=O)c2ccc(Cl)cc2n1
Show InChI InChI=1S/C11H9ClNO5P/c12-7-1-2-8-6(5-19(16,17)18)3-10(11(14)15)13-9(8)4-7/h1-4H,5H2,(H,14,15)(H2,16,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a 6.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283026
PNG
((6,7-Dichloro-2-oxo-1,2-dihydro-quinolin-4-ylmethy...)
Show SMILES OP(O)(=O)Cc1cc(=O)[nH]c2cc(Cl)c(Cl)cc12
Show InChI InChI=1S/C10H8Cl2NO4P/c11-7-2-6-5(4-18(15,16)17)1-10(14)13-9(6)3-8(7)12/h1-3H,4H2,(H,13,14)(H2,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
n/an/a 7.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283025
PNG
(2-Amino-3-[5-iodo-2-(2-phosphono-ethyl)-phenyl]-pr...)
Show SMILES NC(Cc1cc(I)ccc1CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C11H15INO5P/c12-9-2-1-7(3-4-19(16,17)18)8(5-9)6-10(13)11(14)15/h1-2,5,10H,3-4,6,13H2,(H,14,15)(H2,16,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 8.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283028
PNG
(CHEMBL432901 | [2-(7-Chloro-2-oxo-1,2-dihydro-quin...)
Show SMILES OP(O)(=O)CCc1cc(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C11H11ClNO4P/c12-8-1-2-9-7(3-4-18(15,16)17)5-11(14)13-10(9)6-8/h1-2,5-6H,3-4H2,(H,13,14)(H2,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a 2.31E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283031
PNG
((7-Chloro-8-nitro-2-oxo-1,2-dihydro-quinolin-4-ylm...)
Show SMILES O[P+](O)([O-])Cc1cc(=[OH+])[n-]c2c(c(Cl)ccc12)[N+]([O-])=O
Show InChI InChI=1S/C10H8ClN2O6P/c11-7-2-1-6-5(4-20(17,18)19)3-8(14)12-9(6)10(7)13(15)16/h1-3H,4H2,(H3,12,14,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283030
PNG
(7-Chloro-4-(2-phosphono-ethyl)-quinoline-2-carboxy...)
Show SMILES OC(=O)c1cc(CCP(O)(O)=O)c2ccc(Cl)cc2n1
Show InChI InChI=1S/C12H11ClNO5P/c13-8-1-2-9-7(3-4-20(17,18)19)5-11(12(15)16)14-10(9)6-8/h1-2,5-6H,3-4H2,(H,15,16)(H2,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283024
PNG
((7-Chloro-2-oxo-1,2-dihydro-quinolin-4-yl)-phospho...)
Show SMILES OP(O)(=O)c1cc(=O)[nH]c2cc(Cl)ccc12
Show InChI InChI=1S/C9H7ClNO4P/c10-5-1-2-6-7(3-5)11-9(12)4-8(6)16(13,14)15/h1-4H,(H,11,12)(H2,13,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50283022
PNG
((6-Chloro-5-nitro-2-oxo-1,2-dihydro-quinolin-4-ylm...)
Show SMILES O[P+](O)([O-])Cc1cc(=[OH+])[n-]c2ccc(Cl)c([N+]([O-])=O)c12
Show InChI InChI=1S/C10H8ClN2O6P/c11-6-1-2-7-9(10(6)13(15)16)5(3-8(14)12-7)4-20(17,18)19/h1-3H,4H2,(H3,12,14,17,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
n/an/a>1.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity at glycine co-agonist site of rat NMDA receptor

Bioorg Med Chem Lett 4: 2035-2040 (1994)


Article DOI: 10.1016/S0960-894X(01)80558-8
BindingDB Entry DOI: 10.7270/Q2TB17CQ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%