Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403623
(CHEMBL540800)Show SMILES CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(CC(CCC(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C31H41N3O4/c1-30(2,32)29(38)33-26(14-8-11-22-9-4-3-5-10-22)28(37)34-19-17-31(18-20-34)21-23(15-16-27(35)36)24-12-6-7-13-25(24)31/h3-7,9-10,12-13,23,26H,8,11,14-21,32H2,1-2H3,(H,33,38)(H,35,36)/t23?,26-/m1/s1 | Reactome pathway
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PC sid
UniChem
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| Article
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403633
(CHEMBL554852)Show SMILES CCOC(=O)C[C@H]1CC2(CCN(CC2)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C32H40N4O4/c1-4-40-28(37)18-21-19-32(25-11-7-5-9-23(21)25)13-15-36(16-14-32)29(38)27(35-30(39)31(2,3)33)17-22-20-34-26-12-8-6-10-24(22)26/h5-12,20-21,27,34H,4,13-19,33H2,1-3H3,(H,35,39)/t21-,27+/m0/s1 | Reactome pathway
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PC sid
UniChem
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| n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403622
(CHEMBL544769)Show SMILES CCOC(=O)[C@@H]1CC2(CCN(CC2)C(=O)[C@@H](CCCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C31H41N3O4/c1-4-38-28(36)24-21-31(25-15-9-8-14-23(24)25)17-19-34(20-18-31)27(35)26(33-29(37)30(2,3)32)16-10-13-22-11-6-5-7-12-22/h5-9,11-12,14-15,24,26H,4,10,13,16-21,32H2,1-3H3,(H,33,37)/t24-,26-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403629
(CHEMBL553478)Show SMILES CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(C[C@@H](CC(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C30H39N3O4/c1-29(2,31)28(37)32-25(14-8-11-21-9-4-3-5-10-21)27(36)33-17-15-30(16-18-33)20-22(19-26(34)35)23-12-6-7-13-24(23)30/h3-7,9-10,12-13,22,25H,8,11,14-20,31H2,1-2H3,(H,32,37)(H,34,35)/t22-,25-/m1/s1 | Reactome pathway
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PC cid
PC sid
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Similars
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| n/a | n/a | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403632
(CHEMBL558422)Show SMILES CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC2(C[C@@H](CC(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C30H36N4O4/c1-29(2,31)28(38)33-25(15-20-18-32-24-10-6-4-8-22(20)24)27(37)34-13-11-30(12-14-34)17-19(16-26(35)36)21-7-3-5-9-23(21)30/h3-10,18-19,25,32H,11-17,31H2,1-2H3,(H,33,38)(H,35,36)/t19-,25-/m1/s1 | Reactome pathway
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PC sid
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| n/a | n/a | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403637
(CHEMBL555821)Show SMILES CCOC(=O)[C@@H]1CC2(CCN(CC2)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C31H38N4O4/c1-4-39-28(37)23-18-31(24-11-7-5-10-22(23)24)13-15-35(16-14-31)27(36)26(34-29(38)30(2,3)32)17-20-19-33-25-12-8-6-9-21(20)25/h5-12,19,23,26,33H,4,13-18,32H2,1-3H3,(H,34,38)/t23-,26-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403617
(CHEMBL552911)Show SMILES CCOC(=O)[C@@H]1CC2(CCN(CC2)C(=O)[C@@H](COCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C30H39N3O5/c1-4-38-27(35)23-18-30(24-13-9-8-12-22(23)24)14-16-33(17-15-30)26(34)25(32-28(36)29(2,3)31)20-37-19-21-10-6-5-7-11-21/h5-13,23,25H,4,14-20,31H2,1-3H3,(H,32,36)/t23-,25-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403619
(CHEMBL545704)Show SMILES CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(C[C@H](C(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C29H37N3O4/c1-28(2,30)27(36)31-24(14-8-11-20-9-4-3-5-10-20)25(33)32-17-15-29(16-18-32)19-22(26(34)35)21-12-6-7-13-23(21)29/h3-7,9-10,12-13,22,24H,8,11,14-19,30H2,1-2H3,(H,31,36)(H,34,35)/t22-,24+/m0/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403624
(CHEMBL542653)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CN(c3ccccc23)S(C)(=O)=O)CC1 |r| Show InChI InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403630
(CHEMBL558802 | L-162752)Show SMILES CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC2(CCc3ccccc23)CC1 |r| Show InChI InChI=1S/C28H34N4O2/c1-27(2,29)26(34)31-24(17-20-18-30-23-10-6-4-8-21(20)23)25(33)32-15-13-28(14-16-32)12-11-19-7-3-5-9-22(19)28/h3-10,18,24,30H,11-17,29H2,1-2H3,(H,31,34)/t24-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403625
(CHEMBL545002)Show SMILES CCOC(=O)C[C@@H]1CC2(CCN(CC2)C(=O)[C@@H](CCCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C32H43N3O4/c1-4-39-28(36)21-24-22-32(26-15-9-8-14-25(24)26)17-19-35(20-18-32)29(37)27(34-30(38)31(2,3)33)16-10-13-23-11-6-5-7-12-23/h5-9,11-12,14-15,24,27H,4,10,13,16-22,33H2,1-3H3,(H,34,38)/t24-,27-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403626
(CHEMBL544536)Show SMILES CCOC(=O)[C@H]1CC2(CCN(CC2)C(=O)[C@@H](COCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C30H39N3O5/c1-4-38-27(35)23-18-30(24-13-9-8-12-22(23)24)14-16-33(17-15-30)26(34)25(32-28(36)29(2,3)31)20-37-19-21-10-6-5-7-11-21/h5-13,23,25H,4,14-20,31H2,1-3H3,(H,32,36)/t23-,25+/m0/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403631
(CHEMBL557206)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CCc3ccccc23)CC1 |r,@:1,22| Show InChI InChI=1S/C27H35N3O3/c1-26(2,28)25(32)29-23(19-33-18-20-8-4-3-5-9-20)24(31)30-16-14-27(15-17-30)13-12-21-10-6-7-11-22(21)27/h3-11,23H,12-19,28H2,1-2H3,(H,29,32)/t23-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403638
(CHEMBL538008)Show SMILES CCOC(=O)C[C@H]1CC2(CCN(CC2)C(=O)[C@@H](CCCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C32H43N3O4/c1-4-39-28(36)21-24-22-32(26-15-9-8-14-25(24)26)17-19-35(20-18-32)29(37)27(34-30(38)31(2,3)33)16-10-13-23-11-6-5-7-12-23/h5-9,11-12,14-15,24,27H,4,10,13,16-22,33H2,1-3H3,(H,34,38)/t24-,27+/m0/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403621
(CHEMBL553290)Show SMILES CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(C[C@@H](C(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C29H37N3O4/c1-28(2,30)27(36)31-24(14-8-11-20-9-4-3-5-10-20)25(33)32-17-15-29(16-18-32)19-22(26(34)35)21-12-6-7-13-23(21)29/h3-7,9-10,12-13,22,24H,8,11,14-19,30H2,1-2H3,(H,31,36)(H,34,35)/t22-,24-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403628
(L-692585)Show SMILES C[C@@H](O)CNC(C)(C)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O Show InChI InChI=1S/C32H37N7O3/c1-21(40)19-33-32(2,3)18-29(41)34-27-17-16-24-8-4-7-11-28(24)39(31(27)42)20-22-12-14-23(15-13-22)25-9-5-6-10-26(25)30-35-37-38-36-30/h4-15,21,27,33,40H,16-20H2,1-3H3,(H,34,41)(H,35,36,37,38)/t21-,27-/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403635
(CHEMBL553507)Show SMILES CCOC(=O)[C@H]1CC2(CCN(CC2)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C31H38N4O4/c1-4-39-28(37)23-18-31(24-11-7-5-10-22(23)24)13-15-35(16-14-31)27(36)26(34-29(38)30(2,3)32)17-20-19-33-25-12-8-6-9-21(20)25/h5-12,19,23,26,33H,4,13-18,32H2,1-3H3,(H,34,38)/t23-,26+/m0/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 6 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403636
(CHEMBL545003)Show SMILES CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(C[C@H](C(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C28H35N3O5/c1-27(2,29)26(35)30-23(18-36-17-19-8-4-3-5-9-19)24(32)31-14-12-28(13-15-31)16-21(25(33)34)20-10-6-7-11-22(20)28/h3-11,21,23H,12-18,29H2,1-2H3,(H,30,35)(H,33,34)/t21-,23+/m0/s1 | Reactome pathway
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UniChem
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| n/a | n/a | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50049481
((R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)meth...)Show SMILES CC(C)(N)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O Show InChI InChI=1S/C29H31N7O2/c1-29(2,30)17-26(37)31-24-16-15-21-7-3-6-10-25(21)36(28(24)38)18-19-11-13-20(14-12-19)22-8-4-5-9-23(22)27-32-34-35-33-27/h3-14,24H,15-18,30H2,1-2H3,(H,31,37)(H,32,33,34,35)/t24-/m1/s1 | Reactome pathway
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| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403620
(CHEMBL540001)Show SMILES CC(C)(N)C(=O)N[C@@H](CCCc1ccccc1)C(=O)N1CCC2(CCc3ccccc23)CC1 |r,@:1,22| Show InChI InChI=1S/C28H37N3O2/c1-27(2,29)26(33)30-24(14-8-11-21-9-4-3-5-10-21)25(32)31-19-17-28(18-20-31)16-15-22-12-6-7-13-23(22)28/h3-7,9-10,12-13,24H,8,11,14-20,29H2,1-2H3,(H,30,33)/t24-/m0/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403627
(CHEMBL545465)Show SMILES CCOC(=O)[C@H]1CC2(CCN(CC2)C(=O)[C@@H](CCCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C31H41N3O4/c1-4-38-28(36)24-21-31(25-15-9-8-14-23(24)25)17-19-34(20-18-31)27(35)26(33-29(37)30(2,3)32)16-10-13-22-11-6-5-7-12-22/h5-9,11-12,14-15,24,26H,4,10,13,16-21,32H2,1-3H3,(H,33,37)/t24-,26+/m0/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403616
(CHEMBL540805)Show SMILES CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCC2(C[C@H](CC(O)=O)c3ccccc23)CC1 |r| Show InChI InChI=1S/C30H39N3O4/c1-29(2,31)28(37)32-25(14-8-11-21-9-4-3-5-10-21)27(36)33-17-15-30(16-18-33)20-22(19-26(34)35)23-12-6-7-13-24(23)30/h3-7,9-10,12-13,22,25H,8,11,14-20,31H2,1-2H3,(H,32,37)(H,34,35)/t22-,25+/m0/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403618
(CHEMBL538004)Show SMILES CCOC(=O)CCC1CC2(CCN(CC2)C(=O)[C@@H](CCCc2ccccc2)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C33H45N3O4/c1-4-40-29(37)18-17-25-23-33(27-15-9-8-14-26(25)27)19-21-36(22-20-33)30(38)28(35-31(39)32(2,3)34)16-10-13-24-11-6-5-7-12-24/h5-9,11-12,14-15,25,28H,4,10,13,16-23,34H2,1-3H3,(H,35,39)/t25?,28-/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
Growth hormone-releasing hormone receptor
(Rattus norvegicus) | BDBM50403634
(CHEMBL552657)Show SMILES CCOC(=O)C[C@@H]1CC2(CCN(CC2)C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c2ccccc12 |r| Show InChI InChI=1S/C32H40N4O4/c1-4-40-28(37)18-21-19-32(25-11-7-5-9-23(21)25)13-15-36(16-14-32)29(38)27(35-30(39)31(2,3)33)17-22-20-34-26-12-8-6-10-24(22)26/h5-12,20-21,27,34H,4,13-19,33H2,1-3H3,(H,35,39)/t21-,27-/m1/s1 | Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Ability to release growth hormone in a rat pituitary cell assay |
Bioorg Med Chem Lett 7: 2319-2324 (1997)
Article DOI: 10.1016/S0960-894X(97)00421-6
BindingDB Entry DOI: 10.7270/Q23R0V2C |
More data for this
Ligand-Target Pair | |
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