Affinity Data by PubMed id=6292417

PubMed code 6292417

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium- and chloride-dependent GABA transporter 1/GABA transporter 2/GABA transporter 3/betaine transporter (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50003624 ((RS)-nipecotic acid \| CHEMBL277498 \| Nipecotic \| P...) Show SMILES OC(=O)C1CCCNC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223874 (CHEMBL277372) Show SMILES O[C@@H]1CCNC[C@@H]1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223872 (CHEMBL15851) Show SMILES O[C@@H]1CNC[C@@H](C1)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223876 (CHEMBL16226) Show SMILES O[C@H]1CCNC[C@@H]1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223871 (CHEMBL429974) Show SMILES CC(=O)N[C@@H]1CNC[C@@H](C1)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223875 (CHEMBL280511) Show SMILES CC(=O)N[C@@H]1CCNC[C@@H]1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50000106 (4-CARBOXYPIPERIDINE \| CHEMBL279998 \| Piperidine-4-...) Show SMILES OC(=O)C1CCNCC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223877 (CHEMBL16132) Show SMILES O[C@H]1CNCC[C@H]1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Rattus norvegicus)	BDBM50223873 (CHEMBL16357) Show SMILES O[C@@H]1CNCC[C@H]1C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%