Found 6 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50367061
(NALORPHINE | NALORPHINE HYDROCHLORIDE)Show SMILES O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45 |r,c:2,TLB:3:4:22.7.6:18.16.17| Show InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50367061
(NALORPHINE | NALORPHINE HYDROCHLORIDE)Show SMILES O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45 |r,c:2,TLB:3:4:22.7.6:18.16.17| Show InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the presence of sodium(Na+) was determined in mous... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50223880
(CHEMBL610906)Show SMILES [I-].[H][C@]12Oc3c4c(C[C@]5([H])C(C=C[C@@H]1O)[C@]24CC[N+]5(C)CC=C)ccc3O |r,c:10,THB:20:18:10:5.6.7,19:18:10:5.6.7| Show InChI InChI=1S/C20H23NO3.HI/c1-3-9-21(2)10-8-20-13-5-7-16(23)19(20)24-18-15(22)6-4-12(17(18)20)11-14(13)21;/h3-7,13-14,16,19,23H,1,8-11H2,2H3;1H/t13?,14-,16+,19+,20+,21?;/m1./s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50223880
(CHEMBL610906)Show SMILES [I-].[H][C@]12Oc3c4c(C[C@]5([H])C(C=C[C@@H]1O)[C@]24CC[N+]5(C)CC=C)ccc3O |r,c:10,THB:20:18:10:5.6.7,19:18:10:5.6.7| Show InChI InChI=1S/C20H23NO3.HI/c1-3-9-21(2)10-8-20-13-5-7-16(23)19(20)24-18-15(22)6-4-12(17(18)20)11-14(13)21;/h3-7,13-14,16,19,23H,1,8-11H2,2H3;1H/t13?,14-,16+,19+,20+,21?;/m1./s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the absence of sodium(Na+) was determined in mouse... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50223880
(CHEMBL610906)Show SMILES [I-].[H][C@]12Oc3c4c(C[C@]5([H])C(C=C[C@@H]1O)[C@]24CC[N+]5(C)CC=C)ccc3O |r,c:10,THB:20:18:10:5.6.7,19:18:10:5.6.7| Show InChI InChI=1S/C20H23NO3.HI/c1-3-9-21(2)10-8-20-13-5-7-16(23)19(20)24-18-15(22)6-4-12(17(18)20)11-14(13)21;/h3-7,13-14,16,19,23H,1,8-11H2,2H3;1H/t13?,14-,16+,19+,20+,21?;/m1./s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the presence of sodium(Na+) was determined in mous... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Mus musculus (Mouse)-MOUSE) | BDBM50223880
(CHEMBL610906)Show SMILES [I-].[H][C@]12Oc3c4c(C[C@]5([H])C(C=C[C@@H]1O)[C@]24CC[N+]5(C)CC=C)ccc3O |r,c:10,THB:20:18:10:5.6.7,19:18:10:5.6.7| Show InChI InChI=1S/C20H23NO3.HI/c1-3-9-21(2)10-8-20-13-5-7-16(23)19(20)24-18-15(22)6-4-12(17(18)20)11-14(13)21;/h3-7,13-14,16,19,23H,1,8-11H2,2H3;1H/t13?,14-,16+,19+,20+,21?;/m1./s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Concentration required to inhibit the stereospecific [3H]diprenorphine binding Opioid receptors in the presence of sodium(Na+) was determined in mous... |
J Med Chem 25: 1278-80 (1982)
BindingDB Entry DOI: 10.7270/Q25X2C4K |
More data for this
Ligand-Target Pair | |
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