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PubMed code 7401110

Compile data set for download or QSAR
Found 109 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Bos taurus (Bovine))		BDBM50404562
PNG
(CHEMBL353809)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2Oc3ccccc3Oc2c1
Show InChI InChI=1S/C25H33N5O5S/c1-2-17-11-14-30(15-12-17)24(31)19(6-5-13-28-25(26)27)29-36(32,33)18-9-10-22-23(16-18)35-21-8-4-3-7-20(21)34-22/h3-4,7-10,16-17,19,29H,2,5-6,11-15H2,1H3,(H4,26,27,28)
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n/an/a 150n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404544
PNG
(CHEMBL355327)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c3ccccc3oc12
Show InChI InChI=1S/C25H33N5O4S/c1-2-17-12-15-30(16-13-17)24(31)20(9-6-14-28-25(26)27)29-35(32,33)22-11-5-8-19-18-7-3-4-10-21(18)34-23(19)22/h3-5,7-8,10-11,17,20,29H,2,6,9,12-16H2,1H3,(H4,26,27,28)
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n/an/a 200n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404567
PNG
(CHEMBL168621)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2c(c1)oc1ccccc21
Show InChI InChI=1S/C25H33N5O4S/c1-2-17-11-14-30(15-12-17)24(31)21(7-5-13-28-25(26)27)29-35(32,33)18-9-10-20-19-6-3-4-8-22(19)34-23(20)16-18/h3-4,6,8-10,16-17,21,29H,2,5,7,11-15H2,1H3,(H4,26,27,28)
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n/an/a 300n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404563
PNG
(CHEMBL352975)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2Oc3ccccc3Cc2c1
Show InChI InChI=1S/C26H35N5O4S/c1-2-18-11-14-31(15-12-18)25(32)22(7-5-13-29-26(27)28)30-36(33,34)21-9-10-24-20(17-21)16-19-6-3-4-8-23(19)35-24/h3-4,6,8-10,17-18,22,30H,2,5,7,11-16H2,1H3,(H4,27,28,29)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404623
PNG
(CHEMBL168547)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C26H32N6O3S/c1-31(2)23-13-5-11-21-20(23)10-6-14-24(21)36(34,35)30-22(12-7-15-29-26(27)28)25(33)32-16-18-8-3-4-9-19(18)17-32/h3-6,8-11,13-14,22,30H,7,12,15-17H2,1-2H3,(H4,27,28,29)
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n/an/a 670n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404564
PNG
(CHEMBL353701)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCc2ccccc12
Show InChI InChI=1S/C26H32N6O3S/c1-31(2)23-13-5-10-20-19(23)9-6-14-24(20)36(34,35)30-21(11-7-16-29-26(27)28)25(33)32-17-15-18-8-3-4-12-22(18)32/h3-6,8-10,12-14,21,30H,7,11,15-17H2,1-2H3,(H4,27,28,29)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404597
PNG
(CHEMBL169106)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2OCCCOc2c1
Show InChI InChI=1S/C22H35N5O5S/c1-2-16-8-11-27(12-9-16)21(28)18(5-3-10-25-22(23)24)26-33(29,30)17-6-7-19-20(15-17)32-14-4-13-31-19/h6-7,15-16,18,26H,2-5,8-14H2,1H3,(H4,23,24,25)
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n/an/a 5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404632
PNG
(CHEMBL169627)
Show SMILES CCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2CCCCc2c1
Show InChI InChI=1S/C20H33N5O3S/c1-2-3-12-23-19(26)18(9-6-13-24-20(21)22)25-29(27,28)17-11-10-15-7-4-5-8-16(15)14-17/h10-11,14,18,25H,2-9,12-13H2,1H3,(H,23,26)(H4,21,22,24)
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n/an/a 5.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404550
PNG
(CHEMBL169306)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1cccc2CCCCc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C20H31N5O4S/c21-20(22)23-10-4-8-17(19(26)25-11-13-29-14-12-25)24-30(27,28)18-9-3-6-15-5-1-2-7-16(15)18/h3,6,9,17,24H,1-2,4-5,7-8,10-14H2,(H4,21,22,23)
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n/an/a 6.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404566
PNG
(CHEMBL168677)
Show SMILES CC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2OCCCOc2c1
Show InChI InChI=1S/C21H33N5O5S/c1-15-7-10-26(11-8-15)20(27)17(4-2-9-24-21(22)23)25-32(28,29)16-5-6-18-19(14-16)31-13-3-12-30-18/h5-6,14-15,17,25H,2-4,7-13H2,1H3,(H4,22,23,24)
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n/an/a 8.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404583
PNG
(CHEMBL167162)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc3OCCOc3cc2c1
Show InChI InChI=1S/C25H35N5O5S/c1-2-17-7-10-30(11-8-17)24(31)21(4-3-9-28-25(26)27)29-36(32,33)20-6-5-18-15-22-23(16-19(18)14-20)35-13-12-34-22/h5-6,14-17,21,29H,2-4,7-13H2,1H3,(H4,26,27,28)
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404584
PNG
(CHEMBL169775)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCc2ccccc12
Show InChI InChI=1S/C27H34N6O3S/c1-32(2)24-15-5-12-21-20(24)11-6-16-25(21)37(35,36)31-22(13-7-17-30-27(28)29)26(34)33-18-8-10-19-9-3-4-14-23(19)33/h3-6,9,11-12,14-16,22,31H,7-8,10,13,17-18H2,1-2H3,(H4,28,29,30)
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n/an/a 1.70E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404537
PNG
(CHEMBL169419)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2OCCOc2c1
Show InChI InChI=1S/C21H33N5O5S/c1-2-15-7-10-26(11-8-15)20(27)17(4-3-9-24-21(22)23)25-32(28,29)16-5-6-18-19(14-16)31-13-12-30-18/h5-6,14-15,17,25H,2-4,7-13H2,1H3,(H4,22,23,24)
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n/an/a 2.50E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404546
PNG
(CHEMBL166914)
Show SMILES COCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2CCCCc12
Show InChI InChI=1S/C19H31N5O4S/c1-28-13-12-22-18(25)16(9-5-11-23-19(20)21)24-29(26,27)17-10-4-7-14-6-2-3-8-15(14)17/h4,7,10,16,24H,2-3,5-6,8-9,11-13H2,1H3,(H,22,25)(H4,20,21,23)
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n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404631
PNG
(CHEMBL422205)
Show SMILES CCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C20H29N5O3S/c1-2-3-13-23-19(26)17(11-7-14-24-20(21)22)25-29(27,28)18-12-6-9-15-8-4-5-10-16(15)18/h4-6,8-10,12,17,25H,2-3,7,11,13-14H2,1H3,(H,23,26)(H4,21,22,24)
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n/an/a 5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404619
PNG
(CHEMBL352546)
Show SMILES COc1ccc(CNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1
Show InChI InChI=1S/C26H34N6O4S/c1-32(2)23-10-4-8-21-20(23)7-5-11-24(21)37(34,35)31-22(9-6-16-29-26(27)28)25(33)30-17-18-12-14-19(36-3)15-13-18/h4-5,7-8,10-15,22,31H,6,9,16-17H2,1-3H3,(H,30,33)(H4,27,28,29)
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n/an/a 5.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404568
PNG
(CHEMBL354977)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CC2CCCC(C2)C1
Show InChI InChI=1S/C26H38N6O3S/c1-31(2)23-12-4-10-21-20(23)9-5-13-24(21)36(34,35)30-22(11-6-14-29-26(27)28)25(33)32-16-18-7-3-8-19(15-18)17-32/h4-5,9-10,12-13,18-19,22,30H,3,6-8,11,14-17H2,1-2H3,(H4,27,28,29)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404627
PNG
(CHEMBL167349)
Show SMILES CC(C)C1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C26H40N6O3S/c1-18(2)19-13-16-32(17-14-19)25(33)22(10-7-15-29-26(27)28)30-36(34,35)24-12-6-8-20-21(24)9-5-11-23(20)31(3)4/h5-6,8-9,11-12,18-19,22,30H,7,10,13-17H2,1-4H3,(H4,27,28,29)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404593
PNG
(CHEMBL433916)
Show SMILES CC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2CCCCc12
Show InChI InChI=1S/C22H35N5O3S/c1-16-11-14-27(15-12-16)21(28)19(9-5-13-25-22(23)24)26-31(29,30)20-10-4-7-17-6-2-3-8-18(17)20/h4,7,10,16,19,26H,2-3,5-6,8-9,11-15H2,1H3,(H4,23,24,25)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404628
PNG
(CHEMBL353366)
Show SMILES CCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C20H30N6O3S/c1-4-23-19(27)16(10-7-13-24-20(21)22)25-30(28,29)18-12-6-8-14-15(18)9-5-11-17(14)26(2)3/h5-6,8-9,11-12,16,25H,4,7,10,13H2,1-3H3,(H,23,27)(H4,21,22,24)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404602
PNG
(CHEMBL352851)
Show SMILES CCC1CCN(CC1)C(=O)C(CCC[N-]C(N)=[NH2+])NS(=O)(=O)c1cccc2c(cccc12)[N+]([O-])=O
Show InChI InChI=1S/C23H31N6O5S/c1-2-16-11-14-28(15-12-16)22(30)19(8-5-13-26-23(24)25)27-35(33,34)21-10-4-6-17-18(21)7-3-9-20(17)29(31)32/h3-4,6-7,9-10,16,19,27H,2,5,8,11-15H2,1H3,(H3-,24,25,26)/q-1/p+1
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404577
PNG
(CHEMBL353636)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cc(OC)c2ccccc2c1
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-10-13-29(14-11-17)23(30)21(9-6-12-27-24(25)26)28-34(31,32)19-15-18-7-4-5-8-20(18)22(16-19)33-2/h4-5,7-8,15-17,21,28H,3,6,9-14H2,1-2H3,(H4,25,26,27)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404570
PNG
(CHEMBL168905)
Show SMILES CCCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C26H40N6O3S/c1-4-8-19-14-17-32(18-15-19)25(33)22(11-7-16-29-26(27)28)30-36(34,35)24-13-6-9-20-21(24)10-5-12-23(20)31(2)3/h5-6,9-10,12-13,19,22,30H,4,7-8,11,14-18H2,1-3H3,(H4,27,28,29)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404545
PNG
(CHEMBL352789)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1cccc2ccccc12)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C27H33N5O3S/c28-27(29)30-17-7-13-24(26(33)32-18-15-21(16-19-32)20-8-2-1-3-9-20)31-36(34,35)25-14-6-11-22-10-4-5-12-23(22)25/h1-6,8-12,14,21,24,31H,7,13,15-19H2,(H4,28,29,30)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50102210
PNG
(5-Dimethylamino-naphthalene-1-sulfonic acid [4-gua...)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H34N6O3S/c1-28(2)20-12-6-10-18-17(20)9-7-13-21(18)33(31,32)27-19(11-8-14-26-23(24)25)22(30)29-15-4-3-5-16-29/h6-7,9-10,12-13,19,27H,3-5,8,11,14-16H2,1-2H3,(H4,24,25,26)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404594
PNG
(CHEMBL354149)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1cccc2ccccc12)C(=O)N1CCCCCC1
Show InChI InChI=1S/C22H31N5O3S/c23-22(24)25-14-8-12-19(21(28)27-15-5-1-2-6-16-27)26-31(29,30)20-13-7-10-17-9-3-4-11-18(17)20/h3-4,7,9-11,13,19,26H,1-2,5-6,8,12,14-16H2,(H4,23,24,25)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404590
PNG
(CHEMBL167637)
Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C23H33N5O4S/c1-16-9-12-28(13-10-16)22(29)21(4-3-11-26-23(24)25)27-33(30,31)20-8-6-17-5-7-19(32-2)14-18(17)15-20/h5-8,14-16,21,27H,3-4,9-13H2,1-2H3,(H4,24,25,26)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404587
PNG
(CHEMBL355110)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)C(O)=O
Show InChI InChI=1S/C24H33N5O5S/c1-2-16-11-14-29(15-12-16)22(30)20(9-5-13-27-24(25)26)28-35(33,34)21-10-4-6-17-18(21)7-3-8-19(17)23(31)32/h3-4,6-8,10,16,20,28H,2,5,9,11-15H2,1H3,(H,31,32)(H4,25,26,27)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404580
PNG
(CHEMBL166882)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NCC=C
Show InChI InChI=1S/C21H30N6O3S/c1-4-13-24-20(28)17(10-7-14-25-21(22)23)26-31(29,30)19-12-6-8-15-16(19)9-5-11-18(15)27(2)3/h4-6,8-9,11-12,17,26H,1,7,10,13-14H2,2-3H3,(H,24,28)(H4,22,23,25)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404612
PNG
(CHEMBL352359)
Show SMILES CCOc1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CC)CC1
Show InChI InChI=1S/C25H37N5O4S/c1-3-18-13-16-30(17-14-18)24(31)21(10-7-15-28-25(26)27)29-35(32,33)23-12-6-8-19-20(23)9-5-11-22(19)34-4-2/h5-6,8-9,11-12,18,21,29H,3-4,7,10,13-17H2,1-2H3,(H4,26,27,28)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404637
PNG
(CHEMBL262275)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2oc(=O)c(CC)cc2c1
Show InChI InChI=1S/C24H35N5O5S/c1-3-16-9-12-29(13-10-16)22(30)20(6-5-11-27-24(25)26)28-35(32,33)19-7-8-21-18(15-19)14-17(4-2)23(31)34-21/h7-8,14-16,20,28H,3-6,9-13H2,1-2H3,(H4,25,26,27)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404625
PNG
(CHEMBL355417)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C23H33N5O3S/c1-2-17-12-15-28(16-13-17)22(29)20(10-6-14-26-23(24)25)27-32(30,31)21-11-5-8-18-7-3-4-9-19(18)21/h3-5,7-9,11,17,20,27H,2,6,10,12-16H2,1H3,(H4,24,25,26)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404600
PNG
(CHEMBL350603)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cc(OC)c2cc(OC)ccc2c1
Show InChI InChI=1S/C25H37N5O5S/c1-4-17-9-12-30(13-10-17)24(31)22(6-5-11-28-25(26)27)29-36(32,33)20-14-18-7-8-19(34-2)15-21(18)23(16-20)35-3/h7-8,14-17,22,29H,4-6,9-13H2,1-3H3,(H4,26,27,28)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404586
PNG
(CHEMBL169487)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCCCCC1
Show InChI InChI=1S/C25H38N6O3S/c1-30(2)22-14-8-12-20-19(22)11-9-15-23(20)35(33,34)29-21(13-10-16-28-25(26)27)24(32)31-17-6-4-3-5-7-18-31/h8-9,11-12,14-15,21,29H,3-7,10,13,16-18H2,1-2H3,(H4,26,27,28)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404561
PNG
(CHEMBL168594)
Show SMILES CCCCCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C25H40N6O3S/c1-4-5-6-7-8-17-28-24(32)21(14-11-18-29-25(26)27)30-35(33,34)23-16-10-12-19-20(23)13-9-15-22(19)31(2)3/h9-10,12-13,15-16,21,30H,4-8,11,14,17-18H2,1-3H3,(H,28,32)(H4,26,27,29)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404542
PNG
(CHEMBL166858)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2ccc(C)cc12
Show InChI InChI=1S/C24H35N5O3S/c1-3-18-11-14-29(15-12-18)23(30)21(7-5-13-27-24(25)26)28-33(31,32)22-8-4-6-19-10-9-17(2)16-20(19)22/h4,6,8-10,16,18,21,28H,3,5,7,11-15H2,1-2H3,(H4,25,26,27)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404636
PNG
(CHEMBL352304)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccc(OC)cc2c1
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-10-13-29(14-11-17)23(30)22(5-4-12-27-24(25)26)28-34(31,32)21-9-7-18-6-8-20(33-2)15-19(18)16-21/h6-9,15-17,22,28H,3-5,10-14H2,1-2H3,(H4,25,26,27)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404622
PNG
(CHEMBL354563)
Show SMILES CC(C)CNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C22H34N6O3S/c1-15(2)14-26-21(29)18(10-7-13-25-22(23)24)27-32(30,31)20-12-6-8-16-17(20)9-5-11-19(16)28(3)4/h5-6,8-9,11-12,15,18,27H,7,10,13-14H2,1-4H3,(H,26,29)(H4,23,24,25)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404605
PNG
(CHEMBL168401)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C25H38N6O3S/c1-4-18-13-16-31(17-14-18)24(32)21(10-7-15-28-25(26)27)29-35(33,34)23-12-6-8-19-20(23)9-5-11-22(19)30(2)3/h5-6,8-9,11-12,18,21,29H,4,7,10,13-17H2,1-3H3,(H4,26,27,28)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404603
PNG
(CHEMBL168879)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C23H33N5O3S/c1-2-17-11-14-28(15-12-17)22(29)21(8-5-13-26-23(24)25)27-32(30,31)20-10-9-18-6-3-4-7-19(18)16-20/h3-4,6-7,9-10,16-17,21,27H,2,5,8,11-15H2,1H3,(H4,24,25,26)
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TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404543
PNG
(CHEMBL354355)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C29H38N6O3S/c1-34(2)26-14-6-12-24-23(26)11-7-15-27(24)39(37,38)33-25(13-8-18-32-29(30)31)28(36)35-19-16-22(17-20-35)21-9-4-3-5-10-21/h3-7,9-12,14-15,22,25,33H,8,13,16-20H2,1-2H3,(H4,30,31,32)
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n/an/a 1.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404569
PNG
(CHEMBL166585)
Show SMILES CC(C)NC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C21H32N6O3S/c1-14(2)25-20(28)17(10-7-13-24-21(22)23)26-31(29,30)19-12-6-8-15-16(19)9-5-11-18(15)27(3)4/h5-6,8-9,11-12,14,17,26H,7,10,13H2,1-4H3,(H,25,28)(H4,22,23,24)
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n/an/a 1.10E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404574
PNG
(CHEMBL354654)
Show SMILES CCCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C23H36N6O3S/c1-4-5-6-15-26-22(30)19(12-9-16-27-23(24)25)28-33(31,32)21-14-8-10-17-18(21)11-7-13-20(17)29(2)3/h7-8,10-11,13-14,19,28H,4-6,9,12,15-16H2,1-3H3,(H,26,30)(H4,24,25,27)
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n/an/a 1.30E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404581
PNG
(CHEMBL165694)
Show SMILES CC1CCCCN1C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H36N6O3S/c1-17-9-4-5-16-30(17)23(31)20(12-8-15-27-24(25)26)28-34(32,33)22-14-7-10-18-19(22)11-6-13-21(18)29(2)3/h6-7,10-11,13-14,17,20,28H,4-5,8-9,12,15-16H2,1-3H3,(H4,25,26,27)
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n/an/a 1.30E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404608
PNG
(CHEMBL354577)
Show SMILES CCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C21H32N6O3S/c1-4-13-24-20(28)17(10-7-14-25-21(22)23)26-31(29,30)19-12-6-8-15-16(19)9-5-11-18(15)27(2)3/h5-6,8-9,11-12,17,26H,4,7,10,13-14H2,1-3H3,(H,24,28)(H4,22,23,25)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404579
PNG
(CHEMBL168918)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1
Show InChI InChI=1S/C25H37N5O5S/c1-4-17-9-12-30(13-10-17)24(31)21(6-5-11-28-25(26)27)29-36(32,33)20-8-7-18-15-22(34-2)23(35-3)16-19(18)14-20/h7-8,14-17,21,29H,4-6,9-13H2,1-3H3,(H4,26,27,28)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404585
PNG
(CHEMBL170611)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2C(=O)c3ccccc3C(=O)c2c1
Show InChI InChI=1S/C27H33N5O5S/c1-2-17-11-14-32(15-12-17)26(35)23(8-5-13-30-27(28)29)31-38(36,37)18-9-10-21-22(16-18)25(34)20-7-4-3-6-19(20)24(21)33/h3-4,6-7,9-10,16-17,23,31H,2,5,8,11-15H2,1H3,(H4,28,29,30)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404606
PNG
(CHEMBL423271)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2OCCCc2c1
Show InChI InChI=1S/C22H35N5O4S/c1-2-16-9-12-27(13-10-16)21(28)19(6-3-11-25-22(23)24)26-32(29,30)18-7-8-20-17(15-18)5-4-14-31-20/h7-8,15-16,19,26H,2-6,9-14H2,1H3,(H4,23,24,25)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404592
PNG
(CHEMBL352882)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C26H34N6O3S/c1-32(2)23-14-6-12-21-20(23)11-7-15-24(21)36(34,35)31-22(13-8-17-30-26(27)28)25(33)29-18-16-19-9-4-3-5-10-19/h3-7,9-12,14-15,22,31H,8,13,16-18H2,1-2H3,(H,29,33)(H4,27,28,30)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404638
PNG
(CHEMBL168123)
Show SMILES COc1cc2ccc(cc2cc1OC)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C24H35N5O5S/c1-16-8-11-29(12-9-16)23(30)20(5-4-10-27-24(25)26)28-35(31,32)19-7-6-17-14-21(33-2)22(34-3)15-18(17)13-19/h6-7,13-16,20,28H,4-5,8-12H2,1-3H3,(H4,25,26,27)
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n/an/a 1.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404555
PNG
(CHEMBL349991)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCN(C)CC1
Show InChI InChI=1S/C23H35N7O3S/c1-28(2)20-10-4-8-18-17(20)7-5-11-21(18)34(32,33)27-19(9-6-12-26-23(24)25)22(31)30-15-13-29(3)14-16-30/h4-5,7-8,10-11,19,27H,6,9,12-16H2,1-3H3,(H4,24,25,26)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50195751
PNG
(CHEMBL227136 | naphthalene-1-sulfonic acid [(S)-4-...)
Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]S(=O)(=O)c1cccc2ccccc12)-[#6](=O)-[#7]-1-[#6]-[#6]-[#8]-[#6]-[#6]-1
Show InChI InChI=1S/C20H27N5O4S/c21-20(22)23-10-4-8-17(19(26)25-11-13-29-14-12-25)24-30(27,28)18-9-3-6-15-5-1-2-7-16(15)18/h1-3,5-7,9,17,24H,4,8,10-14H2,(H4,21,22,23)/t17-/m0/s1
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404552
PNG
(CHEMBL354913)
Show SMILES CC1CN(CC(C)O1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H36N6O4S/c1-16-14-30(15-17(2)34-16)23(31)20(10-7-13-27-24(25)26)28-35(32,33)22-12-6-8-18-19(22)9-5-11-21(18)29(3)4/h5-6,8-9,11-12,16-17,20,28H,7,10,13-15H2,1-4H3,(H4,25,26,27)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404547
PNG
(CHEMBL167028)
Show SMILES CCCCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H38N6O3S/c1-4-5-6-7-16-27-23(31)20(13-10-17-28-24(25)26)29-34(32,33)22-15-9-11-18-19(22)12-8-14-21(18)30(2)3/h8-9,11-12,14-15,20,29H,4-7,10,13,16-17H2,1-3H3,(H,27,31)(H4,25,26,28)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404549
PNG
(CHEMBL435463)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc(OC)c2ccccc12
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-12-15-29(16-13-17)23(30)20(9-6-14-27-24(25)26)28-34(31,32)22-11-10-21(33-2)18-7-4-5-8-19(18)22/h4-5,7-8,10-11,17,20,28H,3,6,9,12-16H2,1-2H3,(H4,25,26,27)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404578
PNG
(CHEMBL353933)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(Cl)cccc12
Show InChI InChI=1S/C23H32ClN5O3S/c1-2-16-11-14-29(15-12-16)22(30)20(9-5-13-27-23(25)26)28-33(31,32)21-10-4-6-17-18(21)7-3-8-19(17)24/h3-4,6-8,10,16,20,28H,2,5,9,11-15H2,1H3,(H4,25,26,27)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404551
PNG
(CHEMBL168727)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N1CCCCCC1
Show InChI InChI=1S/C22H31N5O3S/c23-22(24)25-13-7-10-20(21(28)27-14-5-1-2-6-15-27)26-31(29,30)19-12-11-17-8-3-4-9-18(17)16-19/h3-4,8-9,11-12,16,20,26H,1-2,5-7,10,13-15H2,(H4,23,24,25)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404634
PNG
(CHEMBL170548)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccc(=O)oc2c1
Show InChI InChI=1S/C22H31N5O5S/c1-2-15-9-12-27(13-10-15)21(29)18(4-3-11-25-22(23)24)26-33(30,31)17-7-5-16-6-8-20(28)32-19(16)14-17/h5-8,14-15,18,26H,2-4,9-13H2,1H3,(H4,23,24,25)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404624
PNG
(CHEMBL167653)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CC1)C(C)(C)C
Show InChI InChI=1S/C27H42N6O3S/c1-27(2,3)19-14-17-33(18-15-19)25(34)22(11-8-16-30-26(28)29)31-37(35,36)24-13-7-9-20-21(24)10-6-12-23(20)32(4)5/h6-7,9-10,12-13,19,22,31H,8,11,14-18H2,1-5H3,(H4,28,29,30)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404626
PNG
(CHEMBL354801)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCSCC1
Show InChI InChI=1S/C22H32N6O3S2/c1-27(2)19-9-3-7-17-16(19)6-4-10-20(17)33(30,31)26-18(8-5-11-25-22(23)24)21(29)28-12-14-32-15-13-28/h3-4,6-7,9-10,18,26H,5,8,11-15H2,1-2H3,(H4,23,24,25)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404616
PNG
(CHEMBL170223)
Show SMILES CCCCN(C)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C23H36N6O3S/c1-5-6-16-29(4)22(30)19(12-9-15-26-23(24)25)27-33(31,32)21-14-8-10-17-18(21)11-7-13-20(17)28(2)3/h7-8,10-11,13-14,19,27H,5-6,9,12,15-16H2,1-4H3,(H4,24,25,26)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404620
PNG
(CHEMBL168720)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N1CCOCC1
Show InChI InChI=1S/C20H27N5O4S/c21-20(22)23-9-3-6-18(19(26)25-10-12-29-13-11-25)24-30(27,28)17-8-7-15-4-1-2-5-16(15)14-17/h1-2,4-5,7-8,14,18,24H,3,6,9-13H2,(H4,21,22,23)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404536
PNG
(CHEMBL354539)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCCCCCC1
Show InChI InChI=1S/C26H40N6O3S/c1-31(2)23-15-9-13-21-20(23)12-10-16-24(21)36(34,35)30-22(14-11-17-29-26(27)28)25(33)32-18-7-5-3-4-6-8-19-32/h9-10,12-13,15-16,22,30H,3-8,11,14,17-19H2,1-2H3,(H4,27,28,29)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404630
PNG
(CHEMBL167075)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(OC)ccc2c1
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-10-13-29(14-11-17)23(30)22(5-4-12-27-24(25)26)28-34(31,32)21-9-7-18-15-20(33-2)8-6-19(18)16-21/h6-9,15-17,22,28H,3-5,10-14H2,1-2H3,(H4,25,26,27)
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n/an/a 2.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404598
PNG
(CHEMBL354492)
Show SMILES CCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C22H34N6O3S/c1-4-5-14-25-21(29)18(11-8-15-26-22(23)24)27-32(30,31)20-13-7-9-16-17(20)10-6-12-19(16)28(2)3/h6-7,9-10,12-13,18,27H,4-5,8,11,14-15H2,1-3H3,(H,25,29)(H4,23,24,26)
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n/an/a 2.10E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404635
PNG
(CHEMBL352547)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(ccc2c1)N(C)C
Show InChI InChI=1S/C25H38N6O3S/c1-4-18-11-14-31(15-12-18)24(32)23(6-5-13-28-25(26)27)29-35(33,34)22-10-8-19-16-21(30(2)3)9-7-20(19)17-22/h7-10,16-18,23,29H,4-6,11-15H2,1-3H3,(H4,26,27,28)
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n/an/a 3.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404575
PNG
(CHEMBL424544)
Show SMILES COc1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C23H33N5O4S/c1-16-11-14-28(15-12-16)22(29)19(8-5-13-26-23(24)25)27-33(30,31)21-10-4-6-17-18(21)7-3-9-20(17)32-2/h3-4,6-7,9-10,16,19,27H,5,8,11-15H2,1-2H3,(H4,24,25,26)
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n/an/a 3.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50064654
PNG
(5-Dimethylamino-naphthalene-1-sulfonic acid [(S)-4...)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H36N6O3S/c1-17-12-15-30(16-13-17)23(31)20(9-6-14-27-24(25)26)28-34(32,33)22-11-5-7-18-19(22)8-4-10-21(18)29(2)3/h4-5,7-8,10-11,17,20,28H,6,9,12-16H2,1-3H3,(H4,25,26,27)/t20-/m0/s1
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n/an/a 3.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404548
PNG
(CHEMBL167165)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(CC)CC
Show InChI InChI=1S/C27H42N6O3S/c1-4-20-15-18-33(19-16-20)26(34)23(12-9-17-30-27(28)29)31-37(35,36)25-14-8-10-21-22(25)11-7-13-24(21)32(5-2)6-3/h7-8,10-11,13-14,20,23,31H,4-6,9,12,15-19H2,1-3H3,(H4,28,29,30)
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n/an/a 3.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404572
PNG
(CHEMBL353390)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCC1
Show InChI InChI=1S/C22H32N6O3S/c1-27(2)19-11-5-9-17-16(19)8-6-12-20(17)32(30,31)26-18(10-7-13-25-22(23)24)21(29)28-14-3-4-15-28/h5-6,8-9,11-12,18,26H,3-4,7,10,13-15H2,1-2H3,(H4,23,24,25)
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n/an/a 3.30E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404601
PNG
(CHEMBL355883)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCN(CC1)C(C)=O
Show InChI InChI=1S/C24H35N7O4S/c1-17(32)30-13-15-31(16-14-30)23(33)20(9-6-12-27-24(25)26)28-36(34,35)22-11-5-7-18-19(22)8-4-10-21(18)29(2)3/h4-5,7-8,10-11,20,28H,6,9,12-16H2,1-3H3,(H4,25,26,27)
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n/an/a 3.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404553
PNG
(CHEMBL168324)
Show SMILES CC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H31N5O3S/c1-16-11-14-27(15-12-16)21(28)19(9-5-13-25-22(23)24)26-31(29,30)20-10-4-7-17-6-2-3-8-18(17)20/h2-4,6-8,10,16,19,26H,5,9,11-15H2,1H3,(H4,23,24,25)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404559
PNG
(CHEMBL169082)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccccc2c1OC
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-12-15-29(16-13-17)23(30)20(9-6-14-27-24(25)26)28-34(31,32)21-11-10-18-7-4-5-8-19(18)22(21)33-2/h4-5,7-8,10-11,17,20,28H,3,6,9,12-16H2,1-2H3,(H4,25,26,27)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404614
PNG
(CHEMBL354443)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NCC1CCCCC1
Show InChI InChI=1S/C25H38N6O3S/c1-31(2)22-14-6-12-20-19(22)11-7-15-23(20)35(33,34)30-21(13-8-16-28-25(26)27)24(32)29-17-18-9-4-3-5-10-18/h6-7,11-12,14-15,18,21,30H,3-5,8-10,13,16-17H2,1-2H3,(H,29,32)(H4,26,27,28)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404588
PNG
(CHEMBL354135)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(OC(C)C)cccc12
Show InChI InChI=1S/C26H39N5O4S/c1-4-19-13-16-31(17-14-19)25(32)22(10-7-15-29-26(27)28)30-36(33,34)24-12-6-8-20-21(24)9-5-11-23(20)35-18(2)3/h5-6,8-9,11-12,18-19,22,30H,4,7,10,13-17H2,1-3H3,(H4,27,28,29)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404607
PNG
(CHEMBL352883)
Show SMILES COCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C21H32N6O4S/c1-27(2)18-10-4-8-16-15(18)7-5-11-19(16)32(29,30)26-17(9-6-12-25-21(22)23)20(28)24-13-14-31-3/h4-5,7-8,10-11,17,26H,6,9,12-14H2,1-3H3,(H,24,28)(H4,22,23,25)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404591
PNG
(CHEMBL169050)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccc(C)cc2c1
Show InChI InChI=1S/C24H35N5O3S/c1-3-18-10-13-29(14-11-18)23(30)22(5-4-12-27-24(25)26)28-33(31,32)21-9-8-19-7-6-17(2)15-20(19)16-21/h6-9,15-16,18,22,28H,3-5,10-14H2,1-2H3,(H4,25,26,27)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404595
PNG
(CHEMBL352631)
Show SMILES COc1cccc2cccc(c12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C23H33N5O4S/c1-16-11-14-28(15-12-16)22(29)18(8-5-13-26-23(24)25)27-33(30,31)20-10-4-7-17-6-3-9-19(32-2)21(17)20/h3-4,6-7,9-10,16,18,27H,5,8,11-15H2,1-2H3,(H4,24,25,26)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404633
PNG
(CHEMBL165767)
Show SMILES COC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H36N6O4S/c1-29(2)21-10-4-8-19-18(21)7-5-11-22(19)35(32,33)28-20(9-6-14-27-24(25)26)23(31)30-15-12-17(34-3)13-16-30/h4-5,7-8,10-11,17,20,28H,6,9,12-16H2,1-3H3,(H4,25,26,27)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404621
PNG
(CHEMBL167100)
Show SMILES CCCCN(CCCC)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C26H42N6O3S/c1-5-7-18-32(19-8-6-2)25(33)22(14-11-17-29-26(27)28)30-36(34,35)24-16-10-12-20-21(24)13-9-15-23(20)31(3)4/h9-10,12-13,15-16,22,30H,5-8,11,14,17-19H2,1-4H3,(H4,27,28,29)
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n/an/a 4.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50403285
PNG
(CHEMBL66348)
Show SMILES CC1CCN(CC1)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C22H31N5O3S/c1-16-10-13-27(14-11-16)21(28)20(7-4-12-25-22(23)24)26-31(29,30)19-9-8-17-5-2-3-6-18(17)15-19/h2-3,5-6,8-9,15-16,20,26H,4,7,10-14H2,1H3,(H4,23,24,25)/t20-/m0/s1
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n/an/a 4.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404599
PNG
(CHEMBL354800)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2CCCCc12
Show InChI InChI=1S/C23H37N5O3S/c1-2-17-12-15-28(16-13-17)22(29)20(10-6-14-26-23(24)25)27-32(30,31)21-11-5-8-18-7-3-4-9-19(18)21/h5,8,11,17,20,27H,2-4,6-7,9-10,12-16H2,1H3,(H4,24,25,26)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404533
PNG
(CHEMBL168772)
Show SMILES CCCCN(C)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H31N5O3S/c1-3-4-14-26(2)20(27)19(10-7-13-24-21(22)23)25-30(28,29)18-12-11-16-8-5-6-9-17(16)15-18/h5-6,8-9,11-12,15,19,25H,3-4,7,10,13-14H2,1-2H3,(H4,22,23,24)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404604
PNG
(CHEMBL165597)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NC1CC1
Show InChI InChI=1S/C21H30N6O3S/c1-27(2)18-9-3-7-16-15(18)6-4-10-19(16)31(29,30)26-17(8-5-13-24-21(22)23)20(28)25-14-11-12-14/h3-4,6-7,9-10,14,17,26H,5,8,11-13H2,1-2H3,(H,25,28)(H4,22,23,24)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404557
PNG
(CHEMBL169626)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NC1CCCCC1
Show InChI InChI=1S/C24H36N6O3S/c1-30(2)21-14-6-12-19-18(21)11-7-15-22(19)34(32,33)29-20(13-8-16-27-24(25)26)23(31)28-17-9-4-3-5-10-17/h6-7,11-12,14-15,17,20,29H,3-5,8-10,13,16H2,1-2H3,(H,28,31)(H4,25,26,27)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404618
PNG
(CHEMBL352961)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)NCc1ccccc1
Show InChI InChI=1S/C25H32N6O3S/c1-31(2)22-14-6-12-20-19(22)11-7-15-23(20)35(33,34)30-21(13-8-16-28-25(26)27)24(32)29-17-18-9-4-3-5-10-18/h3-7,9-12,14-15,21,30H,8,13,16-17H2,1-2H3,(H,29,32)(H4,26,27,28)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404617
PNG
(CHEMBL354511)
Show SMILES CCCCN(C)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H31N5O3S/c1-3-4-15-26(2)20(27)18(12-8-14-24-21(22)23)25-30(28,29)19-13-7-10-16-9-5-6-11-17(16)19/h5-7,9-11,13,18,25H,3-4,8,12,14-15H2,1-2H3,(H4,22,23,24)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404541
PNG
(CHEMBL353154)
Show SMILES CCOCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C22H34N6O4S/c1-4-32-15-14-25-21(29)18(10-7-13-26-22(23)24)27-33(30,31)20-12-6-8-16-17(20)9-5-11-19(16)28(2)3/h5-6,8-9,11-12,18,27H,4,7,10,13-15H2,1-3H3,(H,25,29)(H4,23,24,26)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404571
PNG
(CHEMBL166944)
Show SMILES CCCCN(CC)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H38N6O3S/c1-5-7-17-30(6-2)23(31)20(13-10-16-27-24(25)26)28-34(32,33)22-15-9-11-18-19(22)12-8-14-21(18)29(3)4/h8-9,11-12,14-15,20,28H,5-7,10,13,16-17H2,1-4H3,(H4,25,26,27)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404554
PNG
(CHEMBL352587)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(C)ccc2c1
Show InChI InChI=1S/C24H35N5O3S/c1-3-18-10-13-29(14-11-18)23(30)22(5-4-12-27-24(25)26)28-33(31,32)21-9-8-19-15-17(2)6-7-20(19)16-21/h6-9,15-16,18,22,28H,3-5,10-14H2,1-2H3,(H4,25,26,27)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404573
PNG
(CHEMBL351371)
Show SMILES CCCOc1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CC)CC1
Show InChI InChI=1S/C26H39N5O4S/c1-3-18-35-23-11-5-9-21-20(23)8-6-12-24(21)36(33,34)30-22(10-7-15-29-26(27)28)25(32)31-16-13-19(4-2)14-17-31/h5-6,8-9,11-12,19,22,30H,3-4,7,10,13-18H2,1-2H3,(H4,27,28,29)
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n/an/a 5.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404576
PNG
(CHEMBL167767)
Show SMILES CCOc1cc2ccc(cc2cc1OCC)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(CC)CC1
Show InChI InChI=1S/C27H41N5O5S/c1-4-19-11-14-32(15-12-19)26(33)23(8-7-13-30-27(28)29)31-38(34,35)22-10-9-20-17-24(36-5-2)25(37-6-3)18-21(20)16-22/h9-10,16-19,23,31H,4-8,11-15H2,1-3H3,(H4,28,29,30)
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n/an/a 5.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404558
PNG
(CHEMBL169433)
Show SMILES CCN(CC)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C22H34N6O3S/c1-5-28(6-2)21(29)18(12-9-15-25-22(23)24)26-32(30,31)20-14-8-10-16-17(20)11-7-13-19(16)27(3)4/h7-8,10-11,13-14,18,26H,5-6,9,12,15H2,1-4H3,(H4,23,24,25)
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n/an/a 5.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404615
PNG
(CHEMBL167228)
Show SMILES COCCCNC(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C22H34N6O4S/c1-28(2)19-11-4-9-17-16(19)8-5-12-20(17)33(30,31)27-18(10-6-13-26-22(23)24)21(29)25-14-7-15-32-3/h4-5,8-9,11-12,18,27H,6-7,10,13-15H2,1-3H3,(H,25,29)(H4,23,24,26)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404565
PNG
(CHEMBL169464)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(OC)cccc12
Show InChI InChI=1S/C24H35N5O4S/c1-3-17-12-15-29(16-13-17)23(30)20(9-6-14-27-24(25)26)28-34(31,32)22-11-5-7-18-19(22)8-4-10-21(18)33-2/h4-5,7-8,10-11,17,20,28H,3,6,9,12-16H2,1-2H3,(H4,25,26,27)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404629
PNG
(CHEMBL355469)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2ccc(O)cc2c1
Show InChI InChI=1S/C23H33N5O4S/c1-2-16-9-12-28(13-10-16)22(30)21(4-3-11-26-23(24)25)27-33(31,32)20-8-6-17-5-7-19(29)14-18(17)15-20/h5-8,14-16,21,27,29H,2-4,9-13H2,1H3,(H4,24,25,26)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404589
PNG
(CHEMBL354525)
Show SMILES CC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2CCCCc2c1
Show InChI InChI=1S/C22H35N5O3S/c1-16-10-13-27(14-11-16)21(28)20(7-4-12-25-22(23)24)26-31(29,30)19-9-8-17-5-2-3-6-18(17)15-19/h8-9,15-16,20,26H,2-7,10-14H2,1H3,(H4,23,24,25)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404613
PNG
(CHEMBL166451)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(O)cccc12
Show InChI InChI=1S/C23H33N5O4S/c1-2-16-11-14-28(15-12-16)22(30)19(8-5-13-26-23(24)25)27-33(31,32)21-10-4-6-17-18(21)7-3-9-20(17)29/h3-4,6-7,9-10,16,19,27,29H,2,5,8,11-15H2,1H3,(H4,24,25,26)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404556
PNG
(CHEMBL354388)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCOCC1
Show InChI InChI=1S/C22H32N6O4S/c1-27(2)19-9-3-7-17-16(19)6-4-10-20(17)33(30,31)26-18(8-5-11-25-22(23)24)21(29)28-12-14-32-15-13-28/h3-4,6-7,9-10,18,26H,5,8,11-15H2,1-2H3,(H4,23,24,25)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404610
PNG
(CHEMBL355260)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)C#N
Show InChI InChI=1S/C24H32N6O3S/c1-2-17-11-14-30(15-12-17)23(31)21(9-5-13-28-24(26)27)29-34(32,33)22-10-4-7-19-18(16-25)6-3-8-20(19)22/h3-4,6-8,10,17,21,29H,2,5,9,11-15H2,1H3,(H4,26,27,28)
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n/an/a 6.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404539
PNG
(CHEMBL350285)
Show SMILES CC1CCCN(C1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1cccc2c(cccc12)N(C)C
Show InChI InChI=1S/C24H36N6O3S/c1-17-8-7-15-30(16-17)23(31)20(11-6-14-27-24(25)26)28-34(32,33)22-13-5-9-18-19(22)10-4-12-21(18)29(2)3/h4-5,9-10,12-13,17,20,28H,6-8,11,14-16H2,1-3H3,(H4,25,26,27)
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n/an/a 6.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404534
PNG
(CHEMBL167560)
Show SMILES NC(=N)NCCCC(NS(=O)(=O)c1ccc2CCCCc2c1)C(=O)N1CCCC1
Show InChI InChI=1S/C20H31N5O3S/c21-20(22)23-11-5-8-18(19(26)25-12-3-4-13-25)24-29(27,28)17-10-9-15-6-1-2-7-16(15)14-17/h9-10,14,18,24H,1-8,11-13H2,(H4,21,22,23)
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n/an/a 7.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404596
PNG
(CHEMBL168805)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(CC)ccc2c1
Show InChI InChI=1S/C25H37N5O3S/c1-3-18-11-14-30(15-12-18)24(31)23(6-5-13-28-25(26)27)29-34(32,33)22-10-9-20-16-19(4-2)7-8-21(20)17-22/h7-10,16-18,23,29H,3-6,11-15H2,1-2H3,(H4,26,27,28)
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n/an/a 7.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404540
PNG
(CHEMBL354762)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2CCCCc2c1
Show InChI InChI=1S/C23H37N5O3S/c1-2-17-11-14-28(15-12-17)22(29)21(8-5-13-26-23(24)25)27-32(30,31)20-10-9-18-6-3-4-7-19(18)16-20/h9-10,16-17,21,27H,2-8,11-15H2,1H3,(H4,24,25,26)
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n/an/a 7.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404560
PNG
(CHEMBL166715)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N(C)Cc1ccccc1
Show InChI InChI=1S/C26H34N6O3S/c1-31(2)23-15-7-13-21-20(23)12-8-16-24(21)36(34,35)30-22(14-9-17-29-26(27)28)25(33)32(3)18-19-10-5-4-6-11-19/h4-8,10-13,15-16,22,30H,9,14,17-18H2,1-3H3,(H4,27,28,29)
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n/an/a 7.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404535
PNG
(CHEMBL168763)
Show SMILES COc1ccc2cc(cc(OC)c2c1)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C24H35N5O5S/c1-16-8-11-29(12-9-16)23(30)21(5-4-10-27-24(25)26)28-35(31,32)19-13-17-6-7-18(33-2)14-20(17)22(15-19)34-3/h6-7,13-16,21,28H,4-5,8-12H2,1-3H3,(H4,25,26,27)
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n/an/a 7.50E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404611
PNG
(CHEMBL167045)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCC(C)(C)CC1
Show InChI InChI=1S/C25H38N6O3S/c1-25(2)13-16-31(17-14-25)23(32)20(10-7-15-28-24(26)27)29-35(33,34)22-12-6-8-18-19(22)9-5-11-21(18)30(3)4/h5-6,8-9,11-12,20,29H,7,10,13-17H2,1-4H3,(H4,26,27,28)
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n/an/a 8.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404538
PNG
(CHEMBL167279)
Show SMILES CCC1CCN(CC1)C(=O)C(CCCNC(N)=N)NS(=O)(=O)c1ccc2cc(OC(C)C)ccc2c1
Show InChI InChI=1S/C26H39N5O4S/c1-4-19-11-14-31(15-12-19)25(32)24(6-5-13-29-26(27)28)30-36(33,34)23-10-8-20-16-22(35-18(2)3)9-7-21(20)17-23/h7-10,16-19,24,30H,4-6,11-15H2,1-3H3,(H4,27,28,29)
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n/an/a 8.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
Prothrombin


(Bos taurus (Bovine))		BDBM50404582
PNG
(CHEMBL166785)
Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(=O)N1CCCCCC1
Show InChI InChI=1S/C24H36N6O3S/c1-29(2)21-13-7-11-19-18(21)10-8-14-22(19)34(32,33)28-20(12-9-15-27-24(25)26)23(31)30-16-5-3-4-6-17-30/h7-8,10-11,13-14,20,28H,3-6,9,12,15-17H2,1-2H3,(H4,25,26,27)
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n/an/a 9.00E+9n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bovine thrombin concentration at which clotting time was prolonged 2x over the control.

J Med Chem 23: 830-6 (1980)


BindingDB Entry DOI: 10.7270/Q2FQ9XT7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%