Affinity Data by PubMed id=7914537

PubMed code 7914537

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036914 (4-Naphthalen-1-ylmethyl-1H-imidazole; hydrochlorid...) Show SMILES C(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036913 ((+-)-4-(alpha,2,3-trimethylbenzyl)imidazole \| 4-[1...) Show SMILES CC(c1cnc[nH]1)c1cccc(C)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036910 (4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole \| CHEMBL3...) Show SMILES CC(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036910 (4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole \| CHEMBL3...) Show SMILES CC(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036911 ((1H-Imidazol-4-yl)-naphthalen-1-yl-methanol; hydro...) Show SMILES OC(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036912 (2,2,2-Trifluoro-1-(1H-imidazol-4-yl)-1-naphthalen-...) Show SMILES OC(c1cnc[nH]1)(c1cccc2ccccc12)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036916 (4-(Methoxy-naphthalen-1-yl-methyl)-1H-imidazole; h...) Show SMILES COC(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50036915 ((1H-Imidazol-4-yl)-naphthalen-1-yl-methanone; oxal...) Show SMILES O=C(c1cnc[nH]1)c1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.				J Med Chem 37: 2328-33 (1994) BindingDB Entry DOI: 10.7270/Q26110ZR
Ohio State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%