Affinity Data by PubMed id=8145238

PubMed code 8145238

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type 1 InsP3 receptor isoform S2 (Sus scrofa)	BDBM50040911 ((+)-myo-inositol 1,4,5-trisphosphorothioate \| (-)-...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	7.6	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand.				J Med Chem 37: 868-72 (1994) BindingDB Entry DOI: 10.7270/Q2BG2PN3
					More data for this Ligand-Target Pair
Type 1 InsP3 receptor isoform S2 (Sus scrofa)	BDBM50040911 ((+)-myo-inositol 1,4,5-trisphosphorothioate \| (-)-...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	6.8	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand.				J Med Chem 37: 868-72 (1994) BindingDB Entry DOI: 10.7270/Q2BG2PN3
					More data for this Ligand-Target Pair
Type 1 InsP3 receptor isoform S2 (Sus scrofa)	BDBM50040909 (D-3-amino-3-deoxy-myo-inositol 1,4,5-trisphosphoro...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.65E+3	n/a	n/a	n/a	n/a	7.6	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 7.6 using [3H]Ins(1,4,5)P3 as the radioligand.				J Med Chem 37: 868-72 (1994) BindingDB Entry DOI: 10.7270/Q2BG2PN3
					More data for this Ligand-Target Pair
Type 1 InsP3 receptor isoform S2 (Sus scrofa)	BDBM50040909 (D-3-amino-3-deoxy-myo-inositol 1,4,5-trisphosphoro...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.11E+3	n/a	n/a	n/a	n/a	6.8	n/a
Mayo Foundation for Medical Education and Research Curated by ChEMBL					Assay Description Binding affinity against IP3 receptor in pig cerebellar membranes at a pH of 6.8 using [3H]Ins(1,4,5)P3 as the radioligand.				J Med Chem 37: 868-72 (1994) BindingDB Entry DOI: 10.7270/Q2BG2PN3
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%