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PubMed code 8340919

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
S-adenosylmethionine decarboxylase proenzyme


(Rattus norvegicus)		BDBM50368644
PNG
(CHEMBL1202793 | Sardomozide chloride)
Show SMILES NC(=N)NN=C1CCc2c1cccc2C(N)=N |w:4.3|
Show InChI InChI=1S/C11H14N6/c12-10(13)8-3-1-2-7-6(8)4-5-9(7)16-17-11(14)15/h1-3H,4-5H2,(H3,12,13)(H4,14,15,17)
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n/an/a 5n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liver

J Med Chem 36: 2168-71 (1993)


BindingDB Entry DOI: 10.7270/Q24Q7VM5
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
S-adenosylmethionine decarboxylase proenzyme


(Rattus norvegicus)		BDBM50368645
PNG
(CHEMBL1202792)
Show SMILES [#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c1cccc(n1)-[#6](-[#7])=[#7] |w:2.2|
Show InChI InChI=1S/C9H13N7/c1-5(15-16-9(12)13)6-3-2-4-7(14-6)8(10)11/h2-4H,1H3,(H3,10,11)(H4,12,13,16)
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n/an/a 10n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liver

J Med Chem 36: 2168-71 (1993)


BindingDB Entry DOI: 10.7270/Q24Q7VM5
More data for this
Ligand-Target Pair
S-adenosylmethionine decarboxylase proenzyme


(Rattus norvegicus)		BDBM50044330
PNG
((2Z)-2-((2E)-2-{[(E)-amino(imino)methyl]hydrazono}...)
Show SMILES [#6]-[#6](-[#6]=[#7]-[#7]-[#6](-[#7])=[#7])=[#7]\[#7]=[#6](/[#7])-[#7] |w:8.8,3.3|
Show InChI InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liver

J Med Chem 36: 2168-71 (1993)


BindingDB Entry DOI: 10.7270/Q24Q7VM5
More data for this
Ligand-Target Pair
S-adenosylmethionine decarboxylase proenzyme


(Rattus norvegicus)		BDBM50368643
PNG
(CHEMBL1202794)
Show SMILES [#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c1cc(ccn1)-[#6](-[#7])=[#7] |w:2.2|
Show InChI InChI=1S/C9H13N7/c1-5(15-16-9(12)13)7-4-6(8(10)11)2-3-14-7/h2-4H,1H3,(H3,10,11)(H4,12,13,16)
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n/an/a 5.10E+3n/an/an/an/an/an/a



Ciba-Geigy AG

Curated by ChEMBL


Assay Description
Inhibitory activity against S- adenosylmethionine decarboxylase (SAMDC) from rat liver

J Med Chem 36: 2168-71 (1993)


BindingDB Entry DOI: 10.7270/Q24Q7VM5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%