Affinity Data by PubMed id=8496907

PubMed code 8496907

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50047259 (4-(1-(1H-imidazol-1-yl)vinyl)benzonitrile \| 4-(1-I...) Show SMILES C=C(c1ccc(cc1)C#N)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50047261 (5-(1H-imidazol-1-yl)-7,8-dihydronaphthalene-2-carb...) Show SMILES N#Cc1ccc2C(=CCCc2c1)n1ccnc1 \|c:6\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9920 ((S)Fadrozole \| 4-[(5S)-5,6,7,8-tetrahydroimidazo[1...) Show SMILES N#Cc1ccc(cc1)[C@@H]1CCCc2cncn12 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50047260 (4,4'-((1H-imidazol-1-yl)methylene)dibenzonitrile \|...) Show SMILES N#Cc1ccc(cc1)C(c1ccc(cc1)C#N)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50047264 (4-((4-bromophenylimino)(1H-imidazol-1-yl)methyl)be...) Show SMILES Brc1ccc(cc1)\N=C(/c1ccc(cc1)C#N)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50047263 (4-[5-(4-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50047262 ((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...) Show SMILES N#Cc1ccc(cc1)[C@H]1CCCc2cncn12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione \| 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Ltd Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A1				J Med Chem 36: 1393-400 (1993) BindingDB Entry DOI: 10.7270/Q2ZK5FR9
CIBA-GEIGY Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%