Affinity Data by PubMed id=8558530

PubMed code 8558530

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50048580 (CHEMBL29835 \| Indol-1-yl-propyl-pyridin-4-yl-amine...) Show SMILES CCCN(c1ccncc1)n1ccc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-pirenzepine binding against Muscarinic acetylcholine receptor M1 from rat cortical membranes using in vitr...				J Med Chem 39: 582-7 (1996) Article DOI: 10.1021/jm950644v BindingDB Entry DOI: 10.7270/Q27080HJ
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50048612 (CHEMBL350442 \| Methyl-pyridin-4-yl-(2-vinyl-pyrrol...) Show SMILES CN(c1ccncc1)n1cccc1C=C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]-pirenzepine binding against Muscarinic acetylcholine receptor M1 from rat cortical membranes using in vitr...				J Med Chem 39: 582-7 (1996) Article DOI: 10.1021/jm950644v BindingDB Entry DOI: 10.7270/Q27080HJ
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50048580 (CHEMBL29835 \| Indol-1-yl-propyl-pyridin-4-yl-amine...) Show SMILES CCCN(c1ccncc1)n1ccc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of Acetylcholinesterase from rat striatum				J Med Chem 39: 582-7 (1996) Article DOI: 10.1021/jm950644v BindingDB Entry DOI: 10.7270/Q27080HJ
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Rattus norvegicus (rat))	BDBM50048612 (CHEMBL350442 \| Methyl-pyridin-4-yl-(2-vinyl-pyrrol...) Show SMILES CN(c1ccncc1)n1cccc1C=C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Compound was tested in vitro for the inhibition of Acetylcholinesterase from rat striatum				J Med Chem 39: 582-7 (1996) Article DOI: 10.1021/jm950644v BindingDB Entry DOI: 10.7270/Q27080HJ
Hoechst-Roussel Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%