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PubMed code 9089334

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))		BDBM50057300
PNG
((2R,3R,4R,5R)-5-(6-Amino-purin-9-yl)-2-hydroxymeth...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1S
Show InChI InChI=1S/C10H13N5O3S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(19)6(17)4(1-16)18-10/h2-4,6-7,10,16-17,19H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
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PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of human erbB-2 receptor tyrosine kinase

J Med Chem 40: 1130-5 (1997)


Article DOI: 10.1021/jm960380s
BindingDB Entry DOI: 10.7270/Q23X85RT
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM14487
PNG
((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
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KEGG
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PubMed
n/an/a 1.95E+5n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of erbB-1 receptor tyrosine kinase from A431 human epidermoidcarcinoma cells

J Med Chem 40: 1130-5 (1997)


Article DOI: 10.1021/jm960380s
BindingDB Entry DOI: 10.7270/Q23X85RT
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50057300
PNG
((2R,3R,4R,5R)-5-(6-Amino-purin-9-yl)-2-hydroxymeth...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1S
Show InChI InChI=1S/C10H13N5O3S/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(19)6(17)4(1-16)18-10/h2-4,6-7,10,16-17,19H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.00E+3n/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Rate constant for inactivation of erbB-1 receptor of A431 human epidermoidcarcinoma cells

J Med Chem 40: 1130-5 (1997)


Article DOI: 10.1021/jm960380s
BindingDB Entry DOI: 10.7270/Q23X85RT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%