Affinity Data by PubMed id=9526557

PubMed code 9526557

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005044 ((2R,4S)-5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005075 ((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001263 (5,7-Dichloro-4-hydroxy-3-(4-hydroxy-phenyl)-1H-qui...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005034 (7-Chloro-5-iodo-4-oxo-1,4-dihydro-quinoline-2-carb...) Show SMILES OC(=O)c1cc(O)c2c(I)cc(Cl)cc2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50004952 (3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%