Affinity Data by PubMed id=9599245

PubMed code 9599245

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50082395 ((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...) Show SMILES CCC[C@@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50082395 ((3S,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...) Show SMILES CCC[C@@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50147851 ((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...) Show SMILES CCC[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50147851 ((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-3-propyl-pipe...) Show SMILES CCC[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86699 (4-ARA-127) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24.8	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099288 ((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...) Show SMILES COC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454928 (CHEMBL2115481) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454929 (CHEMBL2115080) Show SMILES [H][C@@]1(CCN(C)C[C@@H]1CO)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454928 (CHEMBL2115481) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50454929 (CHEMBL2115080) Show SMILES [H][C@@]1(CCN(C)C[C@@H]1CO)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM86699 (4-ARA-127) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85.2	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50178672 ((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...) Show SMILES COC(=O)[C@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099288 ((3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...) Show SMILES COC(=O)[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50064495 (CHEMBL291652 \| [(R)-4-(4-Chloro-phenyl)-1-methyl-p...) Show SMILES CN1CC[C@H](C(CO)C1)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	442	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50147844 (Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	461	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50178672 ((3R,4R)-methyl 4-(4-chlorophenyl)-1-methylpiperidi...) Show SMILES COC(=O)[C@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	653	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50064498 ((S)-1-Methyl-4-phenyl-piperidine-3-carboxylic acid...) Show SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	769	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50064500 (Acetic acid (R)-4-(4-chloro-phenyl)-1-methyl-piper...) Show SMILES CN1CC[C@H](C(COC(C)=O)C1)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	928	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099296 ((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...) Show SMILES COC(=O)[C@@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranes				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50064500 (Acetic acid (R)-4-(4-chloro-phenyl)-1-methyl-piper...) Show SMILES CN1CC[C@H](C(COC(C)=O)C1)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099296 ((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...) Show SMILES COC(=O)[C@@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high-affinity uptake of [3H]dopamine at dopamine transporter into rat striatal nerve endings (synaptosomes)				J Med Chem 41: 1962-9 (1998) Article DOI: 10.1021/jm980028+ BindingDB Entry DOI: 10.7270/Q2QC0468
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%