Affinity Data by PubMed id=9748366

PubMed code 9748366

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Insulin receptor (Mus musculus)	BDBM50066982 (5-[1,4-Bis-(4-methoxy-benzyl)-1H-imidazol-2-ylamin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin receptor (Mus musculus)	BDBM50066983 (5-[1-(4-Hydroxy-benzyl)-4-(4-methoxy-benzyl)-1H-im...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Mus musculus)	BDBM50066984 (4-(5-(4-hydroxybenzyl)-4-(4-methoxybenzyl)-1-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Mus musculus)	BDBM50066983 (5-[1-(4-Hydroxy-benzyl)-4-(4-methoxy-benzyl)-1H-im...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Mus musculus)	BDBM50066982 (5-[1,4-Bis-(4-methoxy-benzyl)-1H-imidazol-2-ylamin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin receptor (Mus musculus)	BDBM50066984 (4-(5-(4-hydroxybenzyl)-4-(4-methoxybenzyl)-1-methy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibition of insulin receptor mediated mitogenesis of NIH3T3 cells				J Med Chem 41: 3909-11 (1998) Article DOI: 10.1021/jm980294n BindingDB Entry DOI: 10.7270/Q25H7FDR
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%