Affinity Data by PubMed id=9871612

PubMed code 9871612

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50056999 (CHEMBL56367 \| nimesulide) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50069554 (1-Phenothiazin-10-yl-propane-2-thiol \| CHEMBL14903...) Show SMILES CC(S)CN1c2ccccc2Sc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 1 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50069556 (1-Phenothiazin-10-yl-propan-2-ol \| CHEMBL151658) Show SMILES CC(O)CN1c2ccccc2Sc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 1 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50069553 (2-(4-Chloro-phenoxy)-2-methyl-N-(3-phenothiazin-10...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50069554 (1-Phenothiazin-10-yl-propane-2-thiol \| CHEMBL14903...) Show SMILES CC(S)CN1c2ccccc2Sc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50069556 (1-Phenothiazin-10-yl-propan-2-ol \| CHEMBL151658) Show SMILES CC(O)CN1c2ccccc2Sc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50069555 (3-(4-Bromo-phenoxy)-2,2-dimethyl-N-(3-phenothiazin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 2 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50056999 (CHEMBL56367 \| nimesulide) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against human Prostaglandin G/H synthase 1 was determined				Bioorg Med Chem Lett 8: 529-34 (1999) BindingDB Entry DOI: 10.7270/Q2BR8RBX
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%