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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50059715 (4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070314 (7-((3-fluoro-5-(3-hydroxy-6,8-dioxabicyclo[3.2.1]o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070310 (4-Furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070312 (1-Benzyl-4-furan-3-yl-7-[6-(3-hydroxy-6,8-dioxa-bi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070313 (7-[3-Fluoro-5-(3-hydroxy-6,8-dioxa-bicyclo[3.2.1]o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070308 (3-[6-(4-Furan-3-yl-isoquinolin-7-yloxymethyl)-pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070311 (1-Furan-3-yl-6-[6-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50070309 (4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa-bicyclo[3.2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Compound was evaluated for in vitro inhibition of recombinant human 5-lipoxygenase (5-LO) | Bioorg Med Chem Lett 8: 1255-60 (1999) BindingDB Entry DOI: 10.7270/Q29P30SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
