Found 27 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215268
(CHEMBL325211)Show SMILES Nc1cc(OCc2ccccc2)c2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H19FN4O/c26-19-8-6-18(7-9-19)24-22(17-10-12-28-13-11-17)23-20(14-21(27)29-25(23)30-24)31-15-16-4-2-1-3-5-16/h1-14H,15H2,(H3,27,29,30) | PDB
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PC sid
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| n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50067495
(2-(4-Fluoro-phenyl)-4-(3-methoxy-benzyloxy)-3-pyri...)Show SMILES COc1cccc(COc2cc(N)nc3[nH]c(c(-c4ccncc4)c23)-c2ccc(F)cc2)c1 Show InChI InChI=1S/C26H21FN4O2/c1-32-20-4-2-3-16(13-20)15-33-21-14-22(28)30-26-24(21)23(17-9-11-29-12-10-17)25(31-26)18-5-7-19(27)8-6-18/h2-14H,15H2,1H3,(H3,28,30,31) | PDB
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| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215161
(CHEMBL324468)Show SMILES Nc1cc(OCc2ccc(F)cc2)c2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H18F2N4O/c26-18-5-1-15(2-6-18)14-32-20-13-21(28)30-25-23(20)22(16-9-11-29-12-10-16)24(31-25)17-3-7-19(27)8-4-17/h1-13H,14H2,(H3,28,30,31) | PDB
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| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215299
(CHEMBL263536)Show SMILES CCCCOc1cc(N)[nH]c2nc(c(-c3ccncc3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN4O/c1-2-3-12-28-17-13-18(24)26-22-20(17)19(14-8-10-25-11-9-14)21(27-22)15-4-6-16(23)7-5-15/h4-11,13H,2-3,12H2,1H3,(H3,24,26,27) | PDB
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| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215274
(CHEMBL332917)Show SMILES CCCCOc1cc(OC)[nH]c2nc(c(-c3ccncc3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN3O2/c1-3-4-13-29-18-14-19(28-2)26-23-21(18)20(15-9-11-25-12-10-15)22(27-23)16-5-7-17(24)8-6-16/h5-12,14H,3-4,13H2,1-2H3,(H,26,27) | PDB
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| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215267
(CHEMBL115769 | RWJ-68354)Show SMILES COc1cc(N)[nH]c2nc(c(-c3ccncc3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H15FN4O/c1-25-14-10-15(21)23-19-17(14)16(11-6-8-22-9-7-11)18(24-19)12-2-4-13(20)5-3-12/h2-10H,1H3,(H3,21,23,24) | PDB
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| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215272
(CHEMBL115778)Show SMILES Nc1cc(OCCCc2ccccc2)c2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C27H23FN4O/c28-21-10-8-20(9-11-21)26-24(19-12-14-30-15-13-19)25-22(17-23(29)31-27(25)32-26)33-16-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-15,17H,4,7,16H2,(H3,29,31,32) | PDB
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| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215158
(CHEMBL333823)Show SMILES Nc1ccc2c(c([nH]c2n1)-c1cccc(Cl)c1)-c1ccncc1 Show InChI InChI=1S/C18H13ClN4/c19-13-3-1-2-12(10-13)17-16(11-6-8-21-9-7-11)14-4-5-15(20)22-18(14)23-17/h1-10H,(H3,20,22,23) | PDB
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| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215154
(CHEMBL112691)Show SMILES CCCCOc1cc(O)[nH]c2nc(c(-c3ccncc3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H20FN3O2/c1-2-3-12-28-17-13-18(27)25-22-20(17)19(14-8-10-24-11-9-14)21(26-22)15-4-6-16(23)7-5-15/h4-11,13H,2-3,12H2,1H3,(H2,25,26,27) | PDB
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50045333
(CHEBI:90705 | SB-203580)Show SMILES C[S+]([O-])c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 | PDB
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| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215159
(CHEMBL112274)Show SMILES Nc1ccc2c(c([nH]c2n1)-c1ccc(F)c(F)c1)-c1ccncc1 Show InChI InChI=1S/C18H12F2N4/c19-13-3-1-11(9-14(13)20)17-16(10-5-7-22-8-6-10)12-2-4-15(21)23-18(12)24-17/h1-9H,(H3,21,23,24) | PDB
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| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215262
(CHEMBL112273)Show InChI InChI=1S/C18H13FN4/c19-13-3-1-12(2-4-13)17-16(11-7-9-21-10-8-11)14-5-6-15(20)22-18(14)23-17/h1-10H,(H3,20,22,23) | PDB
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| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215160
(CHEMBL320255)Show InChI InChI=1S/C18H13IN4/c19-13-3-1-2-12(10-13)17-16(11-6-8-21-9-7-11)14-4-5-15(20)22-18(14)23-17/h1-10H,(H3,20,22,23) | PDB
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| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215263
(CHEMBL114525)Show SMILES CCOc1ccc(cc1Cl)-c1[nH]c2nc(N)ccc2c1-c1ccncc1 Show InChI InChI=1S/C20H17ClN4O/c1-2-26-16-5-3-13(11-15(16)21)19-18(12-7-9-23-10-8-12)14-4-6-17(22)24-20(14)25-19/h3-11H,2H2,1H3,(H3,22,24,25) | PDB
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215266
(CHEMBL322770)Show SMILES COc1ccc2c(c([nH]c2c1)-c1cccc(I)c1)-c1ccncc1 Show InChI InChI=1S/C20H15IN2O/c1-24-16-5-6-17-18(12-16)23-20(14-3-2-4-15(21)11-14)19(17)13-7-9-22-10-8-13/h2-12,23H,1H3 | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215265
(CHEMBL112396)Show SMILES CC(=O)Nc1ccc2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H15FN4O/c1-12(26)23-17-7-6-16-18(13-8-10-22-11-9-13)19(25-20(16)24-17)14-2-4-15(21)5-3-14/h2-11H,1H3,(H2,23,24,25,26) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215273
(CHEMBL113013)Show SMILES COc1ccc2c(c([nH]c2c1)-c1cccc(Cl)c1)-c1ccncc1 Show InChI InChI=1S/C20H15ClN2O/c1-24-16-5-6-17-18(12-16)23-20(14-3-2-4-15(21)11-14)19(17)13-7-9-22-10-8-13/h2-12,23H,1H3 | PDB
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| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215271
(CHEMBL410857)Show SMILES COc1ccc2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C19H14FN3O/c1-24-16-7-6-15-17(12-8-10-21-11-9-12)18(23-19(15)22-16)13-2-4-14(20)5-3-13/h2-11H,1H3,(H,22,23) | PDB
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| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215264
(CHEMBL263280)Show InChI InChI=1S/C19H14FN3/c20-14-3-1-13(2-4-14)19-18(12-7-9-22-10-8-12)16-6-5-15(21)11-17(16)23-19/h1-11,23H,21H2 | PDB
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| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215270
(CHEMBL326584)Show SMILES Fc1ccc(cc1)-c1[nH]c2nc(NCc3ccccc3)ccc2c1-c1ccncc1 Show InChI InChI=1S/C25H19FN4/c26-20-8-6-19(7-9-20)24-23(18-12-14-27-15-13-18)21-10-11-22(29-25(21)30-24)28-16-17-4-2-1-3-5-17/h1-15H,16H2,(H2,28,29,30) | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215155
(CHEMBL321196)Show SMILES COc1ccc2c(c([nH]c2c1)-c1cccc(F)c1)-c1ccncc1 Show InChI InChI=1S/C20H15FN2O/c1-24-16-5-6-17-18(12-16)23-20(14-3-2-4-15(21)11-14)19(17)13-7-9-22-10-8-13/h2-12,23H,1H3 | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215275
(CHEMBL321851)Show InChI InChI=1S/C18H12FN3/c19-14-5-3-13(4-6-14)17-16(12-7-10-20-11-8-12)15-2-1-9-21-18(15)22-17/h1-11H,(H,21,22) | PDB
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| CHEMBL
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| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215157
(CHEMBL321879)Show SMILES COc1ccc2c(c([nH]c2c1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H15FN2O/c1-24-16-6-7-17-18(12-16)23-20(14-2-4-15(21)5-3-14)19(17)13-8-10-22-11-9-13/h2-12,23H,1H3 | PDB
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antibodypedia
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| CHEMBL
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UniChem
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215261
(CHEMBL326122)Show SMILES CN(C)c1ccc2c(c([nH]c2n1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H17FN4/c1-25(2)17-8-7-16-18(13-9-11-22-12-10-13)19(24-20(16)23-17)14-3-5-15(21)6-4-14/h3-12H,1-2H3,(H,23,24) | PDB
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antibodypedia
antibodypedia
antibodypedia
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GoogleScholar
AffyNet
| CHEMBL
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PC sid
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| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215156
(CHEMBL326923)Show SMILES COc1ccc2c(c([nH]c2c1)-c1ccc(I)cc1)-c1ccncc1 Show InChI InChI=1S/C20H15IN2O/c1-24-16-6-7-17-18(12-16)23-20(14-2-4-15(21)5-3-14)19(17)13-8-10-22-11-9-13/h2-12,23H,1H3 | PDB
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antibodypedia
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215269
(CHEMBL321148)Show InChI InChI=1S/C18H12FN3O/c19-13-3-1-12(2-4-13)17-16(11-7-9-20-10-8-11)14-5-6-15(23)21-18(14)22-17/h1-10H,(H2,21,22,23) | PDB
KEGG
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antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human)) | BDBM50215300
(CHEMBL112036)Show InChI InChI=1S/C19H13FN2/c20-15-7-5-14(6-8-15)19-18(13-9-11-21-12-10-13)16-3-1-2-4-17(16)22-19/h1-12,22H | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells |
Bioorg Med Chem Lett 8: 3335-40 (1998)
BindingDB Entry DOI: 10.7270/Q25T3NNZ |
More data for this
Ligand-Target Pair | |
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