Affinity Data by PubMed id=9925731

PubMed code 9925731

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM20732 ((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description The compound was tested for binding affinity against yeast Heat shock protein HSP 90				J Med Chem 42: 260-6 (1999) Article DOI: 10.1021/jm980403y BindingDB Entry DOI: 10.7270/Q29G5NHQ
University College London Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50347503 (RADICICOL) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description The compound was tested for binding affinity against yeast Heat shock protein HSP 90				J Med Chem 42: 260-6 (1999) Article DOI: 10.1021/jm980403y BindingDB Entry DOI: 10.7270/Q29G5NHQ
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM50347503 (RADICICOL) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description The compound was tested for binding affinity against isolated N-domain of Heat shock protein HSP 90				J Med Chem 42: 260-6 (1999) Article DOI: 10.1021/jm980403y BindingDB Entry DOI: 10.7270/Q29G5NHQ
University College London Curated by ChEMBL					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM20732 ((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	775	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description The compound was tested for binding affinity against isolated N-domain of Heat shock protein HSP 90				J Med Chem 42: 260-6 (1999) Article DOI: 10.1021/jm980403y BindingDB Entry DOI: 10.7270/Q29G5NHQ
University College London Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%