Affinity Data by PubMed id=9934463

PubMed code 9934463

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073210 ((S)-2-Benzyl-3-(formyl-hydroxy-amino)-N-methyl-pro...) Show SMILES CNC(=O)[C@H](CN(O)C=O)Cc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073212 ((S)-2-[(Formyl-hydroxy-amino)-methyl]-4-methyl-pen...) Show SMILES COC(=O)[C@@H](CC(C)C)CN(O)C=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073213 ((R)-2-(Formyl-hydroxy-amino)-4-methyl-pentanoic ac...) Show SMILES COC(=O)[C@@H](CC(C)C)N(O)C=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073214 ((R)-2-Benzyl-3-(formyl-hydroxy-amino)-N-methyl-pro...) Show SMILES CNC(=O)[C@@H](CN(O)C=O)Cc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.82E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073215 ((S)-3-(Acetyl-hydroxy-amino)-2-benzyl-N-methyl-pro...) Show SMILES CNC(=O)[C@H](CN(O)C(C)=O)Cc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.95E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair
Thermolysin (Bacillus thermoproteolyticus)	BDBM50073211 ((S)-2-Benzyl-3-(hydroxy-propionyl-amino)-N-methyl-...) Show SMILES CCC(=O)N(O)C[C@H](Cc1ccccc1)C(=O)NC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin				Bioorg Med Chem Lett 8: 3515-8 (1999) BindingDB Entry DOI: 10.7270/Q2S46R49
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%