Affinity Data by USPatent=US10085986

USPatent US10085986

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287762 (US10085986, Example 5) Show SMILES Oc1cnc(SCc2ccc3ccccc3c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287759 (US10085986, Example 1) Show SMILES Oc1cnc(SCc2cccc(Cl)c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287766 (US10085986, Example 11) Show SMILES Oc1cnc(SCc2cc(F)cc(Cl)c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287765 (US10085986, Example 10) Show SMILES Oc1cnc(SCc2cccc(c2)C(F)(F)F)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287764 (US10085986, Example 9) Show SMILES COc1cccc(CSc2ncc(O)c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287763 (US10085986, Example 6) Show SMILES Oc1cnc(SCc2cccc(F)c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287770 (US10085986, Example 18) Show SMILES Oc1cnc(SCc2cccc(OC(F)F)c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287761 (US10085986, Example 4) Show SMILES Oc1cnc(SCc2ccc(Cl)cc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287760 (US10085986, Example 2) Show SMILES Oc1cnc(SCc2ccccc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287771 (US10085986, Example 20) Show SMILES Oc1cnc(SCc2cccnc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	470	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287767 (US10085986, Example 12) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287769 (US10085986, Example 16) Show SMILES Oc1cnc(SCc2cccc3OCCOc23)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	540	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287773 (US10085986, Example 26) Show SMILES Oc1cnc(SCc2ccc3nccn3c2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	740	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287776 (US10085986, Example 33) Show SMILES Oc1cnc(CCc2ccccc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287768 (US10085986, Example 14) Show SMILES CC(Sc1ncc(O)c(=O)[nH]1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287772 (US10085986, Example 21) Show SMILES Cc1cc(CSc2ncc(O)c(=O)[nH]2)n(C)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287778 (US10085986, Example 35) Show SMILES COc1ccc(CSc2ncc(O)c(=O)n2C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287777 (US10085986, Example 34) Show SMILES Oc1c(nc(SCc2ccccc2)[nH]c1=O)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287774 (US10085986, Example 30) Show SMILES Oc1cnc(CSc2ccccc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair
D-amino-acid oxidase (Homo sapiens (Human))	BDBM287775 (US10085986, Example 31) Show SMILES Oc1cnc(COc2ccccc2)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	7.4	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...				US Patent US10085986 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZWB
Takeda Pharmaceutical Company Limited US Patent					More data for this Ligand-Target Pair

* indicates data uncertainty>20%