Affinity Data by USPatent=US10196353

USPatent US10196353

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM332408 (US10196353, Example 52 \| US11299457, Example 52) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332406 (US10196353, Example 32 \| US11299457, Example 32) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332405 (US10196353, Example 27 \| US11299457, Example 27) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332402 (US10196353, Example 17 \| US11299457, Example 17) Show SMILES CSCC(C)n1c(cc2c(C#N)c(ccc12)C#N)C(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332052 (US10196353, Example 2 \| US11299457, Example 2) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332404 (US10196353, Example 22 \| US11299457, Example 22) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332401 (US10196353, Example 12 \| US11299457, Example 12) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332403 (US10196353, Example 21 \| US11299457, Example 21) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332400 (US10196353, Example 7 \| US11299457, Example 7) Show SMILES CC(CO)n1c(C)cc2c(c(ccc12)C#N)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM332407 (US10196353, Example 43 \| US11299457, Example 43) Show SMILES CC(C)(O)C(C)(C)n1ccc2c(C#N)c(ccc12)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property (No 2) Limited US Patent					Assay Description Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...				US Patent US10196353 (2019) BindingDB Entry DOI: 10.7270/Q2R213G1
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%