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USPatent US8987473

Compile data set for download or QSAR
Found 72 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152051
PNG
(US8987473, 137)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(Cc3n[nH]c(=S)o3)ccc12
Show InChI InChI=1S/C18H14Cl2N4OS/c1-10-12-6-5-11(8-17-21-22-18(26)25-17)7-16(12)24(23-10)9-13-14(19)3-2-4-15(13)20/h2-7H,8-9H2,1H3,(H,22,26)
KEGG

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n/an/a 10n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152041
PNG
(US8987473, 122)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C18H16Cl2N2O2/c1-11-13-7-5-12(6-8-18(23)24)9-17(13)22(21-11)10-14-15(19)3-2-4-16(14)20/h2-5,7,9H,6,8,10H2,1H3,(H,23,24)
KEGG

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n/an/a 10n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152048
PNG
(US8987473, 134)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(Cc3nnn[nH]3)ccc12
Show InChI InChI=1S/C17H14Cl2N6/c1-10-12-6-5-11(8-17-20-23-24-21-17)7-16(12)25(22-10)9-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,20,21,23,24)
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n/an/a 13n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152017
PNG
(US8987473, 82)
Show SMILES Cc1cn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H15Cl2NO2/c1-11-9-21(10-14-15(19)3-2-4-16(14)20)17-7-12(8-18(22)23)5-6-13(11)17/h2-7,9H,8,10H2,1H3,(H,22,23)
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n/an/a 15n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152079
PNG
(US8987473, 183)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(F)(F)C(O)=O
Show InChI InChI=1S/C17H12Cl2F2N2O2/c1-9-11-6-5-10(17(20,21)16(24)25)7-15(11)23(22-9)8-12-13(18)3-2-4-14(12)19/h2-7H,8H2,1H3,(H,24,25)
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n/an/a 15n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152047
PNG
(US8987473, 133)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCCC(O)=O)ccc12
Show InChI InChI=1S/C19H18Cl2N2O2/c1-12-14-9-8-13(4-2-7-19(24)25)10-18(14)23(22-12)11-15-16(20)5-3-6-17(15)21/h3,5-6,8-10H,2,4,7,11H2,1H3,(H,24,25)
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n/an/a 16n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152080
PNG
(US8987473, 185)
Show SMILES Cc1nn(Cc2c(Cl)cccc2C2CC2)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C21H21ClN2O2/c1-13-16-9-5-14(6-10-21(25)26)11-20(16)24(23-13)12-18-17(15-7-8-15)3-2-4-19(18)22/h2-5,9,11,15H,6-8,10,12H2,1H3,(H,25,26)
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n/an/a 17n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152016
PNG
(US8987473, 80)
Show SMILES Cc1cccc(C)c1CN1CC(C)(C)c2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C21H25NO2/c1-14-6-5-7-15(2)17(14)12-22-13-21(3,4)18-9-8-16(10-19(18)22)11-20(23)24/h5-10H,11-13H2,1-4H3,(H,23,24)
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n/an/a 18n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152026
PNG
(US8987473, 97)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C17H14Cl2N2O2/c1-10-12-6-5-11(8-17(22)23)7-16(12)21(20-10)9-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,22,23)
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n/an/a 18n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152011
PNG
(US8987473, 64)
Show SMILES Cc1cn(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H21NO2/c1-13-5-4-6-14(2)18(13)12-21-11-15(3)17-8-7-16(9-19(17)21)10-20(22)23/h4-9,11H,10,12H2,1-3H3,(H,22,23)
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n/an/a 22n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152023
PNG
(US8987473, 89)
Show SMILES Cc1cn(Cc2c(Cl)cccc2Cl)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C19H17Cl2NO2/c1-12-10-22(11-15-16(20)3-2-4-17(15)21)18-9-13(5-7-14(12)18)6-8-19(23)24/h2-5,7,9-10H,6,8,11H2,1H3,(H,23,24)
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n/an/a 23n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152049
PNG
(US8987473, 135)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCc3nnn[nH]3)ccc12
Show InChI InChI=1S/C18H16Cl2N6/c1-11-13-7-5-12(6-8-18-21-24-25-22-18)9-17(13)26(23-11)10-14-15(19)3-2-4-16(14)20/h2-5,7,9H,6,8,10H2,1H3,(H,21,22,24,25)
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n/an/a 23n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152054
PNG
(US8987473, 140)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H16Cl2N2O2/c1-2-16-12-7-6-11(9-18(23)24)8-17(12)22(21-16)10-13-14(19)4-3-5-15(13)20/h3-8H,2,9-10H2,1H3,(H,23,24)
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n/an/a 24n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152015
PNG
(US8987473, 78)
Show SMILES CC1CN(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H23NO2/c1-13-5-4-6-14(2)18(13)12-21-11-15(3)17-8-7-16(9-19(17)21)10-20(22)23/h4-9,15H,10-12H2,1-3H3,(H,22,23)
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n/an/a 24n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152058
PNG
(US8987473, 145)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C19H18Cl2N2O2/c1-2-17-13-8-6-12(7-9-19(24)25)10-18(13)23(22-17)11-14-15(20)4-3-5-16(14)21/h3-6,8,10H,2,7,9,11H2,1H3,(H,24,25)
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n/an/a 26n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152020
PNG
(US8987473, 86)
Show SMILES Cc1cn(Cc2c(F)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H15ClFNO2/c1-11-9-21(10-14-15(19)3-2-4-16(14)20)17-7-12(8-18(22)23)5-6-13(11)17/h2-7,9H,8,10H2,1H3,(H,22,23)
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n/an/a 28n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152013
PNG
(US8987473, 68)
Show SMILES Cc1cccc(C)c1Cn1cc(Cl)c2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C19H18ClNO2/c1-12-4-3-5-13(2)16(12)10-21-11-17(20)15-7-6-14(8-18(15)21)9-19(22)23/h3-8,11H,9-10H2,1-2H3,(H,22,23)
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n/an/a 30n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152042
PNG
(US8987473, 124)
Show SMILES Cc1nn(Cc2csc3ccc(Cl)cc23)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C20H17ClN2O2S/c1-12-16-5-2-13(3-7-20(24)25)8-18(16)23(22-12)10-14-11-26-19-6-4-15(21)9-17(14)19/h2,4-6,8-9,11H,3,7,10H2,1H3,(H,24,25)
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n/an/a 31n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152050
PNG
(US8987473, 136)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(Cc3n[nH]c(=O)o3)ccc12
Show InChI InChI=1S/C18H14Cl2N4O2/c1-10-12-6-5-11(8-17-21-22-18(25)26-17)7-16(12)24(23-10)9-13-14(19)3-2-4-15(13)20/h2-7H,8-9H2,1H3,(H,22,25)
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n/an/a 34n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152056
PNG
(US8987473, 143)
Show SMILES CCc1nn(Cc2c(C)cccc2C)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C19H20N2O2/c1-4-17-15-9-8-14(19(22)23)10-18(15)21(20-17)11-16-12(2)6-5-7-13(16)3/h5-10H,4,11H2,1-3H3,(H,22,23)
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n/an/a 35n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152040
PNG
(US8987473, 121)
Show SMILES Cc1nn(Cc2c(C)cccc2C)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C20H22N2O2/c1-13-5-4-6-14(2)18(13)12-22-19-11-16(8-10-20(23)24)7-9-17(19)15(3)21-22/h4-7,9,11H,8,10,12H2,1-3H3,(H,23,24)
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n/an/a 41n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152027
PNG
(US8987473, 99)
Show SMILES Cc1nn(Cc2cccc(Cl)c2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C17H14Cl2N2O2/c1-10-13-6-5-11(8-16(22)23)7-15(13)21(20-10)9-12-3-2-4-14(18)17(12)19/h2-7H,8-9H2,1H3,(H,22,23)
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n/an/a 41n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152057
PNG
(US8987473, 144)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C17H14Cl2N2O2/c1-2-15-11-7-6-10(17(22)23)8-16(11)21(20-15)9-12-13(18)4-3-5-14(12)19/h3-8H,2,9H2,1H3,(H,22,23)
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n/an/a 42n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152024
PNG
(US8987473, 91)
Show SMILES CCc1cn(Cc2c(C)cccc2C)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C20H21NO2/c1-4-15-11-21(12-18-13(2)6-5-7-14(18)3)19-10-16(20(22)23)8-9-17(15)19/h5-11H,4,12H2,1-3H3,(H,22,23)
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n/an/a 43n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152010
PNG
(US8987473, 61)
Show SMILES Cc1cn(Cc2c(C)cccc2C)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C19H19NO2/c1-12-5-4-6-13(2)17(12)11-20-10-14(3)16-8-7-15(19(21)22)9-18(16)20/h4-10H,11H2,1-3H3,(H,21,22)
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n/an/a 46n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152061
PNG
(US8987473, 148)
Show SMILES OC(=O)Cc1ccc2c(nn(Cc3c(Cl)cccc3Cl)c2c1)C1CC1
Show InChI InChI=1S/C19H16Cl2N2O2/c20-15-2-1-3-16(21)14(15)10-23-17-8-11(9-18(24)25)4-7-13(17)19(22-23)12-5-6-12/h1-4,7-8,12H,5-6,9-10H2,(H,24,25)
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n/an/a 49n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152055
PNG
(US8987473, 142)
Show SMILES CCc1nn(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H22N2O2/c1-4-18-16-9-8-15(11-20(23)24)10-19(16)22(21-18)12-17-13(2)6-5-7-14(17)3/h5-10H,4,11-12H2,1-3H3,(H,23,24)
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n/an/a 50n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152028
PNG
(US8987473, 102)
Show SMILES Cc1nn(Cc2c(C)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H17ClN2O2/c1-11-4-3-5-16(19)15(11)10-21-17-8-13(9-18(22)23)6-7-14(17)12(2)20-21/h3-8H,9-10H2,1-2H3,(H,22,23)
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n/an/a 52n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152073
PNG
(US8987473, 171)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C16H13Cl2N7/c1-2-13-15-14(6-9(7-19-15)16-20-23-24-21-16)25(22-13)8-10-11(17)4-3-5-12(10)18/h3-7H,2,8H2,1H3,(H,20,21,23,24)
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n/an/a 52n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152078
PNG
(US8987473, 182)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)-c1nnn[nH]1
Show InChI InChI=1S/C17H14Cl2N6/c1-2-15-11-7-6-10(17-20-23-24-21-17)8-16(11)25(22-15)9-12-13(18)4-3-5-14(12)19/h3-8H,2,9H2,1H3,(H,20,21,23,24)
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n/an/a 52n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152062
PNG
(US8987473, 149)
Show SMILES Cc1cccc(C)c1Cn1nc(Cl)c2ccc(cc12)C(O)=O
Show InChI InChI=1S/C17H15ClN2O2/c1-10-4-3-5-11(2)14(10)9-20-15-8-12(17(21)22)6-7-13(15)16(18)19-20/h3-8H,9H2,1-2H3,(H,21,22)
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n/an/a 53n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152059
PNG
(US8987473, 146)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(\C=C\C(O)=O)ccc12
Show InChI InChI=1S/C19H16Cl2N2O2/c1-2-17-13-8-6-12(7-9-19(24)25)10-18(13)23(22-17)11-14-15(20)4-3-5-16(14)21/h3-10H,2,11H2,1H3,(H,24,25)/b9-7+
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n/an/a 53n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152018
PNG
(US8987473, 84)
Show SMILES Cc1cn(Cc2cccc(Cl)c2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H15Cl2NO2/c1-11-9-21(10-13-3-2-4-15(19)18(13)20)16-7-12(8-17(22)23)5-6-14(11)16/h2-7,9H,8,10H2,1H3,(H,22,23)
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n/an/a 53n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152070
PNG
(US8987473, 164)
Show SMILES Cc1nn(Cc2c(Cl)cccc2C2CC2)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C18H16ClN7/c1-10-17-16(7-12(8-20-17)18-21-24-25-22-18)26(23-10)9-14-13(11-5-6-11)3-2-4-15(14)19/h2-4,7-8,11H,5-6,9H2,1H3,(H,21,22,24,25)
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n/an/a 55n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152030
PNG
(US8987473, 106)
Show SMILES Cc1nn(Cc2csc3ccc(Cl)cc23)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C19H15ClN2O2S/c1-11-15-4-2-12(7-19(23)24)6-17(15)22(21-11)9-13-10-25-18-5-3-14(20)8-16(13)18/h2-6,8,10H,7,9H2,1H3,(H,23,24)
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n/an/a 55n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152019
PNG
(US8987473, 85)
Show SMILES Cc1cn(Cc2cc(C)ccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H21NO2/c1-13-4-5-14(2)17(8-13)12-21-11-15(3)18-7-6-16(9-19(18)21)10-20(22)23/h4-9,11H,10,12H2,1-3H3,(H,22,23)
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n/an/a 63n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152038
PNG
(US8987473, 119)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C16H12Cl2N2O2/c1-9-11-6-5-10(16(21)22)7-15(11)20(19-9)8-12-13(17)3-2-4-14(12)18/h2-7H,8H2,1H3,(H,21,22)
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n/an/a 65n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152012
PNG
(US8987473, 66)
Show SMILES Cc1nn(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C19H20N2O2/c1-12-5-4-6-13(2)17(12)11-21-18-9-15(10-19(22)23)7-8-16(18)14(3)20-21/h4-9H,10-11H2,1-3H3,(H,22,23)
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n/an/a 67n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152045
PNG
(US8987473, 130)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(=O)CCC(O)=O
Show InChI InChI=1S/C19H16Cl2N2O3/c1-11-13-6-5-12(18(24)7-8-19(25)26)9-17(13)23(22-11)10-14-15(20)3-2-4-16(14)21/h2-6,9H,7-8,10H2,1H3,(H,25,26)
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n/an/a 68n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152025
PNG
(US8987473, 92)
Show SMILES CC(C)c1cn(Cc2c(C)cccc2C)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C21H23NO2/c1-13(2)18-11-22(12-19-14(3)6-5-7-15(19)4)20-10-16(21(23)24)8-9-17(18)20/h5-11,13H,12H2,1-4H3,(H,23,24)
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n/an/a 71n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152043
PNG
(US8987473, 125)
Show SMILES Cc1nn(Cc2c(Cl)cccc2C#N)c2cc(CCC(O)=O)ccc12
Show InChI InChI=1S/C19H16ClN3O2/c1-12-15-7-5-13(6-8-19(24)25)9-18(15)23(22-12)11-16-14(10-21)3-2-4-17(16)20/h2-5,7,9H,6,8,11H2,1H3,(H,24,25)
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n/an/a 72n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152034
PNG
(US8987473, 111)
Show SMILES CC(C(O)=O)c1ccc2c(C)nn(Cc3c(Cl)cccc3Cl)c2c1
Show InChI InChI=1S/C18H16Cl2N2O2/c1-10(18(23)24)12-6-7-13-11(2)21-22(17(13)8-12)9-14-15(19)4-3-5-16(14)20/h3-8,10H,9H2,1-2H3,(H,23,24)
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n/an/a 75n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152060
PNG
(US8987473, 147)
Show SMILES CC(C)c1nn(Cc2c(C)cccc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C21H24N2O2/c1-13(2)21-17-9-8-16(11-20(24)25)10-19(17)23(22-21)12-18-14(3)6-5-7-15(18)4/h5-10,13H,11-12H2,1-4H3,(H,24,25)
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n/an/a 76n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152031
PNG
(US8987473, 107)
Show SMILES Cc1nn(Cc2cccc3ccccc23)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C21H18N2O2/c1-14-18-10-9-15(12-21(24)25)11-20(18)23(22-14)13-17-7-4-6-16-5-2-3-8-19(16)17/h2-11H,12-13H2,1H3,(H,24,25)
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n/an/a 77n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152014
PNG
(US8987473, 75)
Show SMILES Cc1cccc(C)c1CN1CCc2ccc(CC(O)=O)cc12
Show InChI InChI=1S/C19H21NO2/c1-13-4-3-5-14(2)17(13)12-20-9-8-16-7-6-15(10-18(16)20)11-19(21)22/h3-7,10H,8-9,11-12H2,1-2H3,(H,21,22)
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n/an/a 77n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152072
PNG
(US8987473, 170)
Show SMILES CCc1nn(Cc2c(C)cccc2Cl)c2cc(cnc12)C(O)=O
Show InChI InChI=1S/C17H16ClN3O2/c1-3-14-16-15(7-11(8-19-16)17(22)23)21(20-14)9-12-10(2)5-4-6-13(12)18/h4-8H,3,9H2,1-2H3,(H,22,23)
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n/an/a 80n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152071
PNG
(US8987473, 167)
Show SMILES CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(cnc12)C(O)=O
Show InChI InChI=1S/C16H13Cl2N3O2/c1-2-13-15-14(6-9(7-19-15)16(22)23)21(20-13)8-10-11(17)4-3-5-12(10)18/h3-7H,2,8H2,1H3,(H,22,23)
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n/an/a 80n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152021
PNG
(US8987473, 87)
Show SMILES Cc1cn(Cc2ccccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H16ClNO2/c1-12-10-20(11-14-4-2-3-5-16(14)19)17-8-13(9-18(21)22)6-7-15(12)17/h2-8,10H,9,11H2,1H3,(H,21,22)
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n/an/a 88n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152039
PNG
(US8987473, 120)
Show SMILES Cc1nn(Cc2cccc(Cl)c2Cl)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C16H12Cl2N2O2/c1-9-12-6-5-10(16(21)22)7-14(12)20(19-9)8-11-3-2-4-13(17)15(11)18/h2-7H,8H2,1H3,(H,21,22)
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n/an/a 91n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152037
PNG
(US8987473, 117)
Show SMILES Cc1nn(Cc2c(C)cccc2C)c2cc(ccc12)C(O)=O
Show InChI InChI=1S/C18H18N2O2/c1-11-5-4-6-12(2)16(11)10-20-17-9-14(18(21)22)7-8-15(17)13(3)19-20/h4-9H,10H2,1-3H3,(H,21,22)
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n/an/a 91n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152032
PNG
(US8987473, 108)
Show SMILES Cc1nn(Cc2c(C)cc(C)cc2C)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H22N2O2/c1-12-7-13(2)18(14(3)8-12)11-22-19-9-16(10-20(23)24)5-6-17(19)15(4)21-22/h5-9H,10-11H2,1-4H3,(H,23,24)
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n/an/a 94n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152022
PNG
(US8987473, 88)
Show SMILES Cc1cn(Cc2cc3OCOc3cc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C19H16ClNO4/c1-11-8-21(16-4-12(5-19(22)23)2-3-14(11)16)9-13-6-17-18(7-15(13)20)25-10-24-17/h2-4,6-8H,5,9-10H2,1H3,(H,22,23)
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n/an/a 98n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152035
PNG
(US8987473, 112)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(C)(C)C(O)=O
Show InChI InChI=1S/C19H18Cl2N2O2/c1-11-13-8-7-12(19(2,3)18(24)25)9-17(13)23(22-11)10-14-15(20)5-4-6-16(14)21/h4-9H,10H2,1-3H3,(H,24,25)
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n/an/a 98n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152029
PNG
(US8987473, 104)
Show SMILES Cc1nn(Cc2c(F)cccc2Cl)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C17H14ClFN2O2/c1-10-12-6-5-11(8-17(22)23)7-16(12)21(20-10)9-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,22,23)
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n/an/a 101n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152077
PNG
(US8987473, 177)
Show SMILES Cc1cccc(Cl)c1Cn1nc(Cl)c2ncc(cc12)-c1nnn[nH]1
Show InChI InChI=1S/C15H11Cl2N7/c1-8-3-2-4-11(16)10(8)7-24-12-5-9(15-19-22-23-20-15)6-18-13(12)14(17)21-24/h2-6H,7H2,1H3,(H,19,20,22,23)
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n/an/a 104n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152069
PNG
(US8987473, 163)
Show SMILES Cc1nn(Cc2cc(C)ccc2C)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C17H17N7/c1-10-4-5-11(2)14(6-10)9-24-15-7-13(17-19-22-23-20-17)8-18-16(15)12(3)21-24/h4-8H,9H2,1-3H3,(H,19,20,22,23)
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n/an/a 113n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152068
PNG
(US8987473, 160)
Show SMILES Cc1nn(Cc2c(C)cccc2Cl)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C16H14ClN7/c1-9-4-3-5-13(17)12(9)8-24-14-6-11(16-19-22-23-20-16)7-18-15(14)10(2)21-24/h3-7H,8H2,1-2H3,(H,19,20,22,23)
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n/an/a 124n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152075
PNG
(US8987473, 174)
Show SMILES Cc1cccc(Cl)c1Cn1nc(Cl)c2ncc(cc12)C(O)=O
Show InChI InChI=1S/C15H11Cl2N3O2/c1-8-3-2-4-11(16)10(8)7-20-12-5-9(15(21)22)6-18-13(12)14(17)19-20/h2-6H,7H2,1H3,(H,21,22)
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n/an/a 148n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152074
PNG
(US8987473, 172)
Show SMILES OC(=O)c1cnc2c(Cl)nn(Cc3c(Cl)cccc3Cl)c2c1
Show InChI InChI=1S/C14H8Cl3N3O2/c15-9-2-1-3-10(16)8(9)6-20-11-4-7(14(21)22)5-18-12(11)13(17)19-20/h1-5H,6H2,(H,21,22)
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n/an/a 162n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152076
PNG
(US8987473, 175)
Show SMILES Clc1nn(Cc2c(Cl)cccc2Cl)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C14H8Cl3N7/c15-9-2-1-3-10(16)8(9)6-24-11-4-7(14-19-22-23-20-14)5-18-12(11)13(17)21-24/h1-5H,6H2,(H,19,20,22,23)
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n/an/a 163n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152081
PNG
(US8987473, 186)
Show SMILES CC(C)n1c2ccc(cc2n(Cc2c(C)cccc2C)c1=O)C(O)=O
Show InChI InChI=1S/C20H22N2O3/c1-12(2)22-17-9-8-15(19(23)24)10-18(17)21(20(22)25)11-16-13(3)6-5-7-14(16)4/h5-10,12H,11H2,1-4H3,(H,23,24)
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n/an/a 165n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152064
PNG
(US8987473, 152)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2nc(Cc3nnn[nH]3)ccc12
Show InChI InChI=1S/C16H13Cl2N7/c1-9-11-6-5-10(7-15-20-23-24-21-15)19-16(11)25(22-9)8-12-13(17)3-2-4-14(12)18/h2-6H,7-8H2,1H3,(H,20,21,23,24)
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n/an/a 184n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152046
PNG
(US8987473, 132)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CCC(N)=O)ccc12
Show InChI InChI=1S/C18H17Cl2N3O/c1-11-13-7-5-12(6-8-18(21)24)9-17(13)23(22-11)10-14-15(19)3-2-4-16(14)20/h2-5,7,9H,6,8,10H2,1H3,(H2,21,24)
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n/an/a 186n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152067
PNG
(US8987473, 158)
Show SMILES Cc1nn(Cc2cccc(Cl)c2Cl)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C15H11Cl2N7/c1-8-14-12(5-10(6-18-14)15-19-22-23-20-15)24(21-8)7-9-3-2-4-11(16)13(9)17/h2-6H,7H2,1H3,(H,19,20,22,23)
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n/an/a 292n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152063
PNG
(US8987473, 150)
Show SMILES OC(=O)c1ccc2c(nn(Cc3c(Cl)cccc3Cl)c2c1)[N+]#[C-]
Show InChI InChI=1S/C16H9Cl2N3O2/c1-19-15-10-6-5-9(16(22)23)7-14(10)21(20-15)8-11-12(17)3-2-4-13(11)18/h2-7H,8H2,(H,22,23)
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n/an/a 295n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152033
PNG
(US8987473, 109)
Show SMILES Cc1nn(Cc2c(Cl)cccc2C#N)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C18H14ClN3O2/c1-11-14-6-5-12(8-18(23)24)7-17(14)22(21-11)10-15-13(9-20)3-2-4-16(15)19/h2-7H,8,10H2,1H3,(H,23,24)
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n/an/a 335n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152065
PNG
(US8987473, 153)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(cnc12)C(O)=O
Show InChI InChI=1S/C15H11Cl2N3O2/c1-8-14-13(5-9(6-18-14)15(21)22)20(19-8)7-10-11(16)3-2-4-12(10)17/h2-6H,7H2,1H3,(H,21,22)
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n/an/a 361n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152036
PNG
(US8987473, 115)
Show SMILES Cc1nn(Cc2cccc3cccnc23)c2cc(CC(O)=O)ccc12
Show InChI InChI=1S/C20H17N3O2/c1-13-17-8-7-14(11-19(24)25)10-18(17)23(22-13)12-16-5-2-4-15-6-3-9-21-20(15)16/h2-10H,11-12H2,1H3,(H,24,25)
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n/an/a 394n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152066
PNG
(US8987473, 156)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(cnc12)-c1nnn[nH]1
Show InChI InChI=1S/C15H11Cl2N7/c1-8-14-13(5-9(6-18-14)15-19-22-23-20-15)24(21-8)7-10-11(16)3-2-4-12(10)17/h2-6H,7H2,1H3,(H,19,20,22,23)
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n/an/a 438n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152044
PNG
(US8987473, 128)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(ccc12)C(O)C(O)=O
Show InChI InChI=1S/C17H14Cl2N2O3/c1-9-11-6-5-10(16(22)17(23)24)7-15(11)21(20-9)8-12-13(18)3-2-4-14(12)19/h2-7,16,22H,8H2,1H3,(H,23,24)
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n/an/a 576n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152053
PNG
(US8987473, 139)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(CS(O)(=O)=O)ccc12
Show InChI InChI=1S/C16H14Cl2N2O3S/c1-10-12-6-5-11(9-24(21,22)23)7-16(12)20(19-10)8-13-14(17)3-2-4-15(13)18/h2-7H,8-9H2,1H3,(H,21,22,23)
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n/an/a 653n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))
BDBM152052
PNG
(US8987473, 138)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(OCC(O)=O)ccc12
Show InChI InChI=1S/C17H14Cl2N2O3/c1-10-12-6-5-11(24-9-17(22)23)7-16(12)21(20-10)8-13-14(18)3-2-4-15(13)19/h2-7H,8-9H2,1H3,(H,22,23)
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UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 916n/an/an/an/an/an/a



Sato Pharmaceutical Co., Ltd.

US Patent


Assay Description
It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The result...


US Patent US8987473 (2015)


BindingDB Entry DOI: 10.7270/Q23F4NCB
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%