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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200557 (US9227973, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200568 (US9227973, 7B) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200559 (US9227973, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200561 (US9227973, 5 isomer A | US9227973, 6 isomer A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200564 (US9227973, 8C) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200560 (US9227973, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200561 (US9227973, 5 isomer A | US9227973, 6 isomer A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200566 (US9227973, 5 isomer B | US9227973, 6 isomer B) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200558 (US9227973, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200563 (US9227973, 7A) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200565 (BDBM200572 | US9227973, 9 isomer A | US9227973, 9 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200569 (US9227973, 8 isomer D) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200565 (BDBM200572 | US9227973, 9 isomer A | US9227973, 9 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200565 (BDBM200572 | US9227973, 9 isomer A | US9227973, 9 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200565 (BDBM200572 | US9227973, 9 isomer A | US9227973, 9 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay C): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human)) | BDBM200566 (US9227973, 5 isomer B | US9227973, 6 isomer B) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck Sharp & Dohme Corp. US Patent | Assay Description RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 μM isobutyl-me... | US Patent US9227973 (2016) BindingDB Entry DOI: 10.7270/Q2MG7N9K | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
