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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200907 (US9540364, example 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | UniChem | US Patent | n/a | n/a | n/a | n/a | 216 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201001 (US9540364, example 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201010 (US9540364, example 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 50 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201009 (US9540364, example 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 67 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200992 (US9540364, example 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 8 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201005 (US9540364, example 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201006 (US9540364, example 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201008 (US9540364, example 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 34 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201011 (US9540364, example 21) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 38 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201007 (US9540364, example 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 20 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200994 (US9540364, example 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 209 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM201004 (US9540364, example 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200991 (US9540364, example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.29E+3 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200993 (US9540364, example 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 104 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200995 (US9540364, example 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 8 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200998 (US9540364, example 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 34 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200999 (US9540364, example 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 76 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200996 (US9540364, example 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM200997 (US9540364, example 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 33 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9540364 (2017) BindingDB Entry DOI: 10.7270/Q2SB43X2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
