Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337629 (6-Ethyl-4-hydroxypyridazin-3(2H)-one | US9750748, ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337636 (4-Hydroxy-6-isopropylpyridazin-3(2H)-one | US97507...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337631 (6-Cyclopropyl-4-hydroxypyridazin-3(2H)-one | US975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337644 (6-tert-Butyl-4-hydroxypyridazin-3(2H)-one | US9750...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337638 (6-(Dimethylamino)-4-hydroxypyridazin-3(2H)-one | U...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337630 (4-Hydroxy-6-(3-methylbutyl)pyridazin-3(2H)-one | U...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337633 (4-Hydroxy-6-(2-methylpropyl)pyridazin-3(2H)-one | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337642 (6-(Ethyl(methyl)amino)-4-hydroxypyridazin-3(2H)-on...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337641 (4-Hydroxy-6-(methyl(propyl)amino)pyridazin-3(2H)-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337634 (6-Cyclopentyl-4-hydroxypyridazin-3(2H)-one | US975...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337635 (6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337637 (6-(Azetidin-1-yl)-4-hydroxypyridazin-3(2H)-one | U...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337643 (4-Hydroxy-6-(piperidin-1-yl)pyridazin-3(2H)-one | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM337632 (4-Hydroxy-6-(tetrahydro-2H-pyran-4-yl)pyridazin-3(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ... | US Patent US9750748 (2017) BindingDB Entry DOI: 10.7270/Q27M0B1K | |||||||||||
More data for this Ligand-Target Pair |