Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Cell Reactant: | Thrombin | ||
Syringe Reactant: | BDBM32657 | ||
Meas. Tech.: | Isothermal Titration Calorimetry | ||
Entry Date: | 10/13/09 | ||
ΔG°: | -11.1±0.310 (kcal/mole) | ||
pH: | 7.8±n/a | ||
Log10Kb: | n/a | ||
Temperature: | 298.15±n/a (K) | ||
ΔH° : | n/a | ||
ΔHobs : | -9.76±0.120 (kcal/mole) | ||
Ionic Strength: | n/a | ||
yes | |||
Protons Released: | n/a | ||
ΔCp : | n/a | ||
Stoich. Param.: | n/a | ||
ΔS° : | 0±0 (kcal/mole-K) | ||
Comments: | n/a | ||
Citation | Baum, B; Muley, L; Heine, A; Smolinski, M; Hangauer, D; Klebe, G Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin. J Mol Biol391:552-64 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article , ITC RUN data , Solution Info , Data Fit Method , Instrument Info | ||
Thrombin | |||
Source: | Beriplas, CSL Behring | ||
Purity: | n/a | ||
Prep. Method: | n/a | ||
Name: | Prothrombin | ||
Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain | ||
Type: | Protein | ||
Mol. Mass.: | 70029.57 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P00734 | ||
Residue: | 622 | ||
Sequence: |
| ||
BDBM32657 | |||
Source: | n/a | ||
Purity: | n/a | ||
Prep. Method: | n/a | ||
Name | BDBM32657 | ||
Synonyms: | benzamidine- based compound, 6 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H31N5O2 | ||
Mol. Mass. | 469.578 | ||
SMILES | N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N1CCCC1C(=O)NCc1ccc(cc1)C(N)=N |r| | ||
Structure |
Home |
| |
Search |
| |
Deposit |
| |
SiteMap |
| |
About us |
| |
Email us |
| |
Info |
|
©2000 BindingDB. All rights reserved. |