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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Cell Reactant: | Purine nucleoside phosphorylase | ||
| Syringe Reactant: | BDBM50293064 | ||
| Meas. Tech.: | Enzyme Inhibition | ||
| Entry Date: | 03/18/13 | ||
| Δ G ° : | n/a | ||
| pH: | 7.4±0 | ||
| Log10Kb: | n/a | ||
| Temperature: | 300.15±0 (K) | ||
| ΔH° : | -13.3±0.480 (kcal/mole) | ||
| ΔHobs: | n/a | ||
| Ionic Strength: | n/a | ||
| n/a | |||
| Protons Released: | n/a | ||
| ΔCp : | n/a | ||
| Stoich. Param.: | n/a | ||
| ΔS° : | n/a | ||
| Comments: | n/a | ||
| Citation |  Edwards, AA; Mason, JM; Clinch, K; Tyler, PC; Evans, GB; Schramm, VL Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. Biochemistry48:5226-38 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article , ITC RUN data | ||
| Purine nucleoside phosphorylase | |||
| Source: | n/a | ||
| Purity: | n/a | ||
| Prep. Method: | n/a | ||
| Name: | Purine nucleoside phosphorylase | ||
| Synonyms: | Inosine phosphorylase | Inosine-guanosine phosphorylase | NP | PNP | PNPH_HUMAN | Purine nucleoside phosphorylase (PNPase) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 32119.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 289 | ||
| Sequence: |
| ||
| BDBM50293064 | |||
| Source: | n/a | ||
| Purity: | n/a | ||
| Prep. Method: | n/a | ||
| Name | BDBM50293064 | ||
| Synonyms: | 7-({[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | CHEMBL523107 | Immucillins, 10 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C11H16N4O4 | ||
| Mol. Mass. | 268.2691 | ||
| SMILES | OCC(CO)(CO)NCc1c[nH]c2c1nc[nH]c2=O | ||
| Structure | 
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