| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM313178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | S1P1 Binding Assay |
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| IC50 | 119±n/a nM |
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| Citation |  Dyckman, AJ; Dhar, TG; Xiao, H; Gilmore, JL; Yang, MG; Xiao, Z; Marcoux, D Substituted bicyclic compounds US Patent US11058696 Publication Date 7/13/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | Edg1 | Lpb1 | S1PR1_MOUSE | S1pr1 | Sphingosine 1-phosphate receptor 1 | Sphingosine 1-phosphate receptor 1 (S1P1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42663.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O08530 |
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| Residue: | 382 |
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| Sequence: | MVSTSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIM
GWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSH
PQKDDGDNPETIMSSGNVNSSS
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| BDBM313178 |
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| n/a |
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| Name | BDBM313178 |
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| Synonyms: | US10166249, Example 695 | US10709719, Example 696 | US11058696, Example 695 | US11701373, Example 695 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H34NO5P |
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| Mol. Mass. | 411.4721 |
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| SMILES | CCOCCCC1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1 |r| |
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| Structure | 
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