Reaction Details | |||
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![]() | Report a problem with these data | ||
Target | Toll-like receptor 7 | ||
Ligand | BDBM427754 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | TLR7/8/9 Inhibition Reporter Assays | ||
IC50 | 0.280±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Toll-like receptor 7 | |||
Name: | Toll-like receptor 7 | ||
Synonyms: | ORF Names:UNQ248/PRO285 | TLR7 | TLR7_HUMAN | Toll-like receptor 7 (TLR7) | ||
Type: | Enzyme | ||
Mol. Mass.: | 120945.35 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q9NYK1 | ||
Residue: | 1049 | ||
Sequence: |
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BDBM427754 | |||
n/a | |||
Name | BDBM427754 | ||
Synonyms: | US10544143, Example 187 | US10730877, Example 187 | US11053244, Example 187 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H32N6O | ||
Mol. Mass. | 432.5612 | ||
SMILES | COc1cc(cn2ncnc12)-c1[nH]c2ccc(nc2c1C(C)C)C1CCC(CC1)N(C)C |(8.86,1.21,;7.32,1.21,;6.55,-.12,;5.01,-.12,;4.24,-1.46,;5.01,-2.79,;6.55,-2.79,;7.58,-3.93,;8.99,-3.31,;8.83,-1.78,;7.32,-1.46,;2.7,-1.46,;1.8,-2.7,;.33,-2.23,;-1,-3,;-2.34,-2.23,;-2.34,-.69,;-1,.08,;.33,-.69,;1.8,-.21,;2.19,1.28,;1.11,2.37,;3.68,1.68,;-3.67,.08,;-5,-.69,;-6.34,.08,;-6.34,1.62,;-5,2.39,;-3.67,1.62,;-7.67,2.39,;-8.99,1.62,;-7.68,3.93,)| | ||
Structure | ![]() |