| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM517779 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays |
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| EC50 | 100.0±n/a nM |
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| Citation |  Shirude, PS; Chattopadhyay, AK; Wurtz, NR Aryl heterocyclic piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists US Patent US11124494 Publication Date 9/21/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM517779 |
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| n/a |
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| Name | BDBM517779 |
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| Synonyms: | US11124494, Example 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27ClN6O4S |
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| Mol. Mass. | 507.006 |
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| SMILES | CS(=O)(=O)NCC1(CCC1)c1ccc(cc1)N1CCC[C@@H](NC(=O)Nc2cnc(Cl)cn2)C1=O |r| |
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| Structure | 
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