| Reaction Details |
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 | Report a problem with these data |
| Target | B-cell lymphoma 6 protein [5-129] |
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| Ligand | BDBM522238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTRF Assay |
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| IC50 | 49.0±n/a nM |
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| Citation |  Bellenie, BR; Cheung, KM; Davis, OA; Hoelder, S; Huckvale, R; Lloyd, MG 2-quinolone derived inhibitors of BCL6 US Patent US11161839 Publication Date 11/2/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| B-cell lymphoma 6 protein [5-129] |
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| Name: | B-cell lymphoma 6 protein [5-129] |
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| Synonyms: | BCL5 | BCL6 | BCL6_HUMAN | BTB domain-containing protein 27 (BCL-6)(5-129) | LAZ3 | ZBTB27 | ZNF51 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 14310.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 5-129 |
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| Residue: | 125 |
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| Sequence: | ADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQ
LKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKF
IKASE
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| BDBM522238 |
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| n/a |
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| Name | BDBM522238 |
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| Synonyms: | US11161839, Example 19c | US11161839, Example 1v |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21ClN8O2 |
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| Mol. Mass. | 488.929 |
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| SMILES | CNC(=O)c1cc(Nc2ccc3n(C)c(=O)cc(NC(C)c4ncccn4)c3c2)c(C#N)c(Cl)n1 |
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| Structure | 
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